Gene Symbol | PLD1 |
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Entrez Gene | 5337 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | phospholipase D1, phosphatidylcholine-specific |
Other Description | choline phosphatase 1|phosphatidylcholine-hydrolyzing phospholipase D1|phospholipase D1 |
Swissprots | Q13393 |
Accessions | EAW78480 Q13393 AB209907 BAD93144 AJ276230 CAB76564 AK026225 AK091897 BC068976 AAH68976 BX648900 DA325526 DA464847 HQ257981 ADR82735 U38545 AAB49031 XM_005247533 XP_005247590 XM_005247534 XP_005247591 XM_011512897 XP_011511199 XM_011512898 XP_011511200 XM_011512899 XP_011511201 XR_924146 NM_001130081 NP_001123553 NM_002662 NP_002653 |
Function | Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Late endosome membrane {ECO:0000250}; Lipid- anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. |
Tissue Specificity | Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine. {ECO:0000269|PubMed:9582313}. |
Top Pathways | Sphingolipid signaling pathway, Choline metabolism in cancer, cAMP signaling pathway, Glutamatergic synapse, Endocytosis |
Human Phospholipase D1 protein fragment - ab114568 from Abcam
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Recombinant Human PLD1 Protein - H00005337-Q01 from Novus Biologicals
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PLD1 Peptide - P2038 from Novus Biologicals
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PLD1-Antibody-C-term-Blocking-peptide - BP11670b from Abgent, a WuXi AppTec company
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PLD1-Antibody-N-term-Blocking-peptide - BP12199a from Abgent, a WuXi AppTec company
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PLD1-Antibody-N-term-Blocking-Peptide - BP6377a from Abgent, a WuXi AppTec company
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Phospholipase D1 / PLD1 - H00005337-Q01-10 from Acris Antibodies
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Phospholipase D1 / PLD1 - H00005337-Q01-25 from Acris Antibodies
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PLD1 fusion protein - Ag11945 from Proteintech Group
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PLD1 fusion protein - Ag13227 from Proteintech Group
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Recombinant Human PLD1, GST-tagged - PLD1-27923TH from Creative Biomart
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Recombinant Human PLD1, GST-tagged - PLD1-1770H from Creative Biomart
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Recombinant Phospholipase D (PLD) - RPC049Hu01 from Uscn Life Science Inc.
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PC-PLD1 (K556) Peptide - BS1686P from Bioworld Technology
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Recombinant Phospholipase D (PLD) - RPC049Hu01 from Cloud-clone
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Recombinant Human Phospholipase D1(PLD1) ,partial - CSB-YP614406HU CSB-EP614406HU CSB-BP614406HU CSB-MP614406HU from Cusabio
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Phospholipase D1 (PLD1), partial, Recombinant Protein - MBS1318752 from MyBioSource
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PLD1 Recombinant Protein Antigen - NBP2-34078PEP from Novus Biologicals
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PLD1 Peptide, Human - M34GP11912H from Creative Peptides
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PLD1 Recombinant Protein (OPCD06264) - OPCD06264 from Aviva Systems Biology
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