PLD1

Gene Symbol PLD1
Entrez Gene 5337
Alt Symbol -
Species Human
Gene Type protein-coding
Description phospholipase D1, phosphatidylcholine-specific
Other Description choline phosphatase 1|phosphatidylcholine-hydrolyzing phospholipase D1|phospholipase D1
Swissprots Q13393
Accessions EAW78480 Q13393 AB209907 BAD93144 AJ276230 CAB76564 AK026225 AK091897 BC068976 AAH68976 BX648900 DA325526 DA464847 HQ257981 ADR82735 U38545 AAB49031 XM_005247533 XP_005247590 XM_005247534 XP_005247591 XM_011512897 XP_011511199 XM_011512898 XP_011511200 XM_011512899 XP_011511201 XR_924146 NM_001130081 NP_001123553 NM_002662 NP_002653
Function Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, perinuclear region {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Late endosome membrane {ECO:0000250}; Lipid- anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Tissue Specificity Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine. {ECO:0000269|PubMed:9582313}.
Top Pathways Sphingolipid signaling pathway, Choline metabolism in cancer, cAMP signaling pathway, Glutamatergic synapse, Endocytosis

PC-PLD1 CRISPR/Cas9 KO Plasmid (h) - sc-402528 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC-PLD1 HDR Plasmid (h) - sc-402528-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC-PLD1 Double Nickase Plasmid (h) - sc-402528-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC-PLD1 Double Nickase Plasmid (h2) - sc-402528-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC-PLD1 CRISPR Activation Plasmid (h) - sc-402528-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC-PLD1 CRISPR Activation Plasmid (h2) - sc-402528-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC-PLD1 Lentiviral Activation Particles (h) - sc-402528-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC-PLD1 Lentiviral Activation Particles (h2) - sc-402528-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PC-PLD1 siRNA (h) - sc-44000 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PC-PLD1 shRNA Plasmid (h) - sc-44000-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PC-PLD1 shRNA (h) Lentiviral Particles - sc-44000-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PLD1 RNAi - H00005337-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU064141 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16936 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16936 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLD1 siRNA (Human) - CRH3577 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLD1 (NM_002662.4) - SHH377332 from Creative biogene

Category siRNA
Species Reactivities Human

PLD1 shRNA Plasmid (Human) - CHH3577 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLD1 miRNA 3'UTR clone - MiUTR4H-TG12160 from Creative biogene

Species Reactivities Human
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