BMP1

Gene Symbol BMP1
Entrez Gene 649
Alt Symbol OI13, PCOLC, PCP, PCP2, TLD
Species Human
Gene Type protein-coding
Description bone morphogenetic protein 1
Other Description mammalian tolloid protein|procollagen C-endopeptidase|procollagen C-proteinase 3
Swissprots Q13872 Q99421 Q14874 Q99422 Q99423 D3DSR0 Q13292 B2RN46 P13497 A8K6F5
Accessions AAD15059 EAW63697 EAW63698 EAW63702 P13497 AB012098 BAA76306 AB209590 BAD92827 AF318323 AAL55830 AK126396 AK226123 AK291620 BAF84309 AL137746 BC002593 BC009305 BC032105 BC044626 BC101763 AAI01764 BC101765 AAI01766 BC136679 AAI36680 BC142953 AAI42954 BC143338 AAI43339 BC144365 BC144366 BE619065 BU627735 DA720194 DA864391 DR004420 L35278 AAC41703 L35279 AAC41710 M22488 AAA51833 U50330 AAA93462 Y08723 CAA69973 Y08724 CAA69974 Y08725 CAA69975 XM_006716386 XP_006716449 XM_011544617 XP_011542919 XR_428315 XR_949458 NM_001199 NP_001190 NM_006129 NP_006120 NR_033403 NR_033404 NM_006128 NM_006130 NM_006131 NM_006132
Function Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX.
Subcellular Location Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:12637569}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:12637569}. Note=Co- localizes with POSTN in the Golgi. {ECO:0000250}.
Tissue Specificity Ubiquitous.

BMP-1 (H-300) - sc-33200 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BMP-1 (H-300): sc-33200. Western blot analysis of BMP-1 expression in NIH/3T3 whole cell lysate.

BMP-1 (A-20) - sc-27324 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BMP-1 (A-20): sc-27324. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

BMP-1 (N-20) - sc-16962 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BMP-1 (N-20): sc-16962. Western blot analysis of BMP-1 expression in NIH/3T3 whole cell lysate.

BMP-1 (Y-20) - sc-27326 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BMP1 antibody - ab118520 from Abcam

Prices $388.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of BMP1 expression in Formalin-Fixed, Paraffin-Embedded Human Skin using 10 µg/ml ab118520 followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-BMP1 antibody - ab38953 from Abcam

Prices $372.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BMP1 antibody - ab65918 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BMP1 antibody (ab65918) at 1/1000 dilutionLane 1 : High molecular weight markersLane 2 : HDFn in Complete Medium, treatment with IL 1-Beta at 30 µlLane 3 : HDFn in Complete Medium, treatment with TNF-alpha at 30 µlLane 4 : HDFn in Complete Medium, treatment with IL 1-Beta at 35 µlLane 5 : HDFn in Complete Medium, treatment with TNF-alpha at 35 µlLane 6 : HDFn in Complete Medium, treatment with IL 1-Beta at 40 µlLane 7 : HDFn in Complete Medium, treatment with TNF-alpha at 40 µl

Anti-BMP1 antibody - ab167316 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-BMP1 antibody (ab167316) at 1 µg/mlLane 1 : BMP1-transfected 293T cell line lysate Lane 2 : Non-transfected lysateLysates/proteins at 15 µl per lane.

Anti-BMP1 antibody [3E9] - ab156768 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E9
All lanes : Anti-BMP1 antibody [3E9] (ab156768) at 1/4000 dilutionLane 1 : Lysate from HEK293T cells transfected with an empty vectorLane 2 : Lysate from HEK293T cells transfected with a vector bearing BMP1Lysates/proteins at 5 µg per lane.

Anti-BMP1 antibody - Aminoterminal end - ab38951 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BMP1 antibody - Carboxyterminal end - ab65919 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BMP1 antibody - Carboxyterminal end (ab65919) at 1/1000 dilutionLane 1 : High molecular weight markersLane 2 : HDFn treated with TNF-alpha in Complete Medium at 20 µlLane 3 : HDFn treated with TNF-alpha in Complete Medium at 25 µlLane 4 : HDFn treated with TNF-alpha in Complete Medium at 30 µl

Anti-BMP1 antibody - CUB-2 domain - ab38952 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab38952 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab38952, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-BMP1 Antibody - LS-C4206 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (N-Terminus) - LS-C35157 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody - LS-C96160 from LifeSpan Bioscience

Prices $345.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (N-Terminus) - LS-C127057 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (aa121-730) - LS-C149860 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BMP1 Antibody (C-Terminus, AP) - LS-C275498 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (C-Terminus, APC) - LS-C275500 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (C-Terminus, Biotin) - LS-C275501 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (C-Terminus, FITC) - LS-C275502 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (C-Terminus, Azide-free, HRP) - LS-C275503 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (C-Terminus, PE) - LS-C275504 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (aa610-843, Biotin) - LS-C297551 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BMP1 Antibody (aa856-982, Biotin) - LS-C297552 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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