Gene Symbol |
BMP1
|
Entrez Gene |
649
|
Alt Symbol |
OI13, PCOLC, PCP, PCP2, TLD
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
bone morphogenetic protein 1
|
Other Description |
mammalian tolloid protein|procollagen C-endopeptidase|procollagen C-proteinase 3
|
Swissprots |
Q13872 Q99421 Q14874 Q99422 Q99423 D3DSR0 Q13292 B2RN46 P13497 A8K6F5
|
Accessions |
AAD15059 EAW63697 EAW63698 EAW63702 P13497 AB012098 BAA76306 AB209590 BAD92827 AF318323 AAL55830 AK126396 AK226123 AK291620 BAF84309 AL137746 BC002593 BC009305 BC032105 BC044626 BC101763 AAI01764 BC101765 AAI01766 BC136679 AAI36680 BC142953 AAI42954 BC143338 AAI43339 BC144365 BC144366 BE619065 BU627735 DA720194 DA864391 DR004420 L35278 AAC41703 L35279 AAC41710 M22488 AAA51833 U50330 AAA93462 Y08723 CAA69973 Y08724 CAA69974 Y08725 CAA69975 XM_006716386 XP_006716449 XM_011544617 XP_011542919 XR_428315 XR_949458 NM_001199 NP_001190 NM_006129 NP_006120 NR_033403 NR_033404 NM_006128 NM_006130 NM_006131 NM_006132
|
Function |
Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX.
|
Subcellular Location |
Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:12637569}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:12637569}. Note=Co- localizes with POSTN in the Golgi. {ECO:0000250}.
|
Tissue Specificity |
Ubiquitous.
|