| Gene Symbol |
Polr2j
|
| Entrez Gene |
20022
|
| Alt Symbol |
14.5kDa, Polr2i, Rpb11a, Rpo2-4
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
polymerase (RNA) II (DNA directed) polypeptide J
|
| Other Description |
DNA-directed RNA polymerase II 13.3 kDa polypeptide|DNA-directed RNA polymerase II subunit J|DNA-directed RNA polymerase II subunit RPB11|RNA polymerase II 13.3 kDa subunit|RNA polymerase II 4 (14 kDa subunit)|RNA polymerase II subunit B11|RNA polymerase II subunit RPB14|RPB14|polymerase (RNA) II (DNA directed) polypeptide I
|
| Swissprots |
O08740
|
| Accessions |
EDL19323 O08740 AK158610 BAE34581 AK158644 BAE34594 BC042939 AAH42939 D85818 BAA19918 DV065741 NM_011293 NP_035423
|
| Function |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Top Pathways |
Huntington's disease, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism
|