| Gene Symbol |
TCN1
|
| Entrez Gene |
6947
|
| Alt Symbol |
HC, TC-1, TC1, TCI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transcobalamin I (vitamin B12 binding protein, R binder family)
|
| Other Description |
haptocorin|haptocorrin|protein R|transcobalamin-1
|
| Swissprots |
A8KAC5 P20061 Q8WV77
|
| Accessions |
EAW73861 P20061 AK292990 BAF85679 BC018632 BC156607 AAI56608 BM769693 BM818792 BP370727 DQ892807 ABM83733 DQ896054 ABM87053 J05068 AAA61058 NM_001062 NP_001053
|
| Function |
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils. {ECO:0000269|PubMed:2777761}.
|