PLP1

Gene Symbol	PLP1
Entrez Gene	5354
Alt Symbol	GPM6C, HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2
Species	Human
Gene Type	protein-coding
Description	proteolipid protein 1
Other Description	lipophilin|major myelin proteolipid protein|myelin proteolipid protein
Swissprots	Q502Y1 Q6FHZ6 P60201
Accessions	AAA60350 AAB26927 AAB26928 AAD13880 BAA02577 BAA04110 CAA07364 CAA47050 EAW54690 EAW54691 EAW54692 EAW54693 EAW54694 P60201 AI205189 AK128782 AK292728 BAF85417 AK295374 BAG58333 AK295388 BAG58342 AK308966 AK309239 AK312340 BAG35261 AV731932 BC002665 AAH02665 BC095452 AAH95452 BQ717999 BQ723748 BT019601 AAV38408 BT019602 AAV38409 BX445448 CA389667 CR536542 CAG38779 DA299940 DC342197 DC342996 EB387051 M17085 AAA60118 M27110 AAA60117 M54927 AAA59565 NM_000533 NP_000524 NM_001128834 NP_001122306 NM_001305004 NP_001291933 NM_199478 NP_955772
Function	This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:24103481}; Multi-pass membrane protein {ECO:0000269|PubMed:24103481}. Myelin membrane {ECO:0000250}. Note=Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PLP CRISPR/Cas9 KO Plasmid (h) - sc-401663 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PLP HDR Plasmid (h) - sc-401663-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLP Double Nickase Plasmid (h) - sc-401663-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLP Double Nickase Plasmid (h2) - sc-401663-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLP CRISPR Activation Plasmid (h) - sc-401663-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PLP CRISPR Activation Plasmid (h2) - sc-401663-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PLP Lentiviral Activation Particles (h) - sc-401663-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLP Lentiviral Activation Particles (h2) - sc-401663-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLP siRNA (h) - sc-42034 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PLP shRNA Plasmid (h) - sc-42034-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PLP shRNA (h) Lentiviral Particles - sc-42034-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Myelin PLP RNAi - H00005354-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU067901 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16996 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16996 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10804 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10804

PLP1 siRNA (Human) - CRH3592 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Myelin PLP RNAi - H00005354-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human PLP1 (NM_000533.3) - SHH378012 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PLP1(NM_000533.3) - SHR123162 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PLP1(NM_199478.1) - SHR123198 from Creative biogene Category siRNA Species Reactivities Human

Human PLP1 siRNA - orb264094 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PLP1 shRNA Plasmid (Human) - CHH3592 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PLP1 miRNA 3'UTR clone - MiUTR1H-08014 from Creative biogene Species Reactivities Human

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