| Gene Symbol |
KCNA10
|
| Entrez Gene |
3744
|
| Alt Symbol |
Kcn1, Kv1.8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, voltage gated shaker related subfamily A, member 10
|
| Other Description |
cyclic GMP gated potassium channel|potassium voltage-gated channel subfamily A member 10|potassium voltage-gated channel, shaker-related subfamily, member 10|voltage-gated potassium channel subunit Kv1.8
|
| Swissprots |
Q16322
|
| Accessions |
AAB34663 AAC51333 EAW56454 Q16322 BC074990 AAH74990 CA309199 NM_005549 NP_005540
|
| Function |
Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP. {ECO:0000269|PubMed:10836990}.
|
| Subcellular Location |
Membrane {ECO:0000269|PubMed:10836990}; Multi-pass membrane protein {ECO:0000269|PubMed:10836990}.
|
| Tissue Specificity |
Detected in kidney, in proximal tubules, glomerular endothelium, in vascular endothelium and in smooth muscle cells. {ECO:0000269|PubMed:12444201}.
|