Gene Symbol | KCNA10 |
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Entrez Gene | 3744 |
Alt Symbol | Kcn1, Kv1.8 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated shaker related subfamily A, member 10 |
Other Description | cyclic GMP gated potassium channel|potassium voltage-gated channel subfamily A member 10|potassium voltage-gated channel, shaker-related subfamily, member 10|voltage-gated potassium channel subunit Kv1.8 |
Swissprots | Q16322 |
Accessions | AAB34663 AAC51333 EAW56454 Q16322 BC074990 AAH74990 CA309199 NM_005549 NP_005540 |
Function | Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP. {ECO:0000269|PubMed:10836990}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:10836990}; Multi-pass membrane protein {ECO:0000269|PubMed:10836990}. |
Tissue Specificity | Detected in kidney, in proximal tubules, glomerular endothelium, in vascular endothelium and in smooth muscle cells. {ECO:0000269|PubMed:12444201}. |
KCNA10 CRISPR/Cas9 KO Plasmid (h) - sc-410843 from Santa Cruz Biotechnology
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KCNA10 HDR Plasmid (h) - sc-410843-HDR from Santa Cruz Biotechnology
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KCNA10 Double Nickase Plasmid (h) - sc-410843-NIC from Santa Cruz Biotechnology
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KCNA10 Double Nickase Plasmid (h2) - sc-410843-NIC-2 from Santa Cruz Biotechnology
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KCNA10 CRISPR Activation Plasmid (h) - sc-410843-ACT from Santa Cruz Biotechnology
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KCNA10 CRISPR Activation Plasmid (h2) - sc-410843-ACT-2 from Santa Cruz Biotechnology
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KCNA10 Lentiviral Activation Particles (h) - sc-410843-LAC from Santa Cruz Biotechnology
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KCNA10 Lentiviral Activation Particles (h2) - sc-410843-LAC-2 from Santa Cruz Biotechnology
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KCNA10 siRNA (h) - sc-62527 from Santa Cruz Biotechnology
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KCNA10 shRNA Plasmid (h) - sc-62527-SH from Santa Cruz Biotechnology
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KCNA10 shRNA (h) Lentiviral Particles - sc-62527-V from Santa Cruz Biotechnology
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KCNA10 RNAi - H00003744-R01 from Novus Biologicals
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MISSION® esiRNA - EHU055161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10917 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10917 from Sigma-Aldrich
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KCNA10 siRNA (Human) - CRH2520 from Cohesion Biosciences
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KCNA10, siRNA - MBS8200777 from MyBioSource
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shRNA set against Human KCNA10 (NM_005549.2) - SHH322687 from Creative biogene
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shRNA set against Human KCNA10(NM_005549.2) - SHL188166 from Creative biogene
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KCNA10 shRNA Plasmid (Human) - CHH2520 from Cohesion Biosciences
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KCNA10 miRNA 3'UTR clone - MiUTR1H-05093 from Creative biogene
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