Gene Symbol |
ARHGAP31
|
Entrez Gene |
57514
|
Alt Symbol |
AOS1, CDGAP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
Rho GTPase activating protein 31
|
Other Description |
Cdc42 GTPase-activating protein|rho GTPase-activating protein 31
|
Swissprots |
Q9ULL6 Q2M1Z3
|
Accessions |
EAW79573 EAW79574 Q2M1Z3 AB033030 BAA86518 AK026689 AK293726 BAH11580 BC112163 AAI12164 BC112165 AAI12166 BM970175 HQ258543 ADR83297 XM_005247671 XP_005247728 XM_006713714 XP_006713777 NM_020754 NP_065805
|
Function |
Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration. {ECO:0000269|PubMed:12192056, ECO:0000269|PubMed:16519628}.
|
Subcellular Location |
Cell projection, lamellipodium. Cell junction, focal adhesion {ECO:0000250}.
|