Gene Symbol | ARHGAP31 |
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Entrez Gene | 57514 |
Alt Symbol | AOS1, CDGAP |
Species | Human |
Gene Type | protein-coding |
Description | Rho GTPase activating protein 31 |
Other Description | Cdc42 GTPase-activating protein|rho GTPase-activating protein 31 |
Swissprots | Q9ULL6 Q2M1Z3 |
Accessions | EAW79573 EAW79574 Q2M1Z3 AB033030 BAA86518 AK026689 AK293726 BAH11580 BC112163 AAI12164 BC112165 AAI12166 BM970175 HQ258543 ADR83297 XM_005247671 XP_005247728 XM_006713714 XP_006713777 NM_020754 NP_065805 |
Function | Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration. {ECO:0000269|PubMed:12192056, ECO:0000269|PubMed:16519628}. |
Subcellular Location | Cell projection, lamellipodium. Cell junction, focal adhesion {ECO:0000250}. |
CdGAP CRISPR/Cas9 KO Plasmid (h) - sc-408930 from Santa Cruz Biotechnology
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CdGAP HDR Plasmid (h) - sc-408930-HDR from Santa Cruz Biotechnology
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CdGAP Double Nickase Plasmid (h) - sc-408930-NIC from Santa Cruz Biotechnology
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CdGAP Double Nickase Plasmid (h2) - sc-408930-NIC-2 from Santa Cruz Biotechnology
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CdGAP CRISPR Activation Plasmid (h) - sc-408930-ACT from Santa Cruz Biotechnology
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CdGAP CRISPR Activation Plasmid (h2) - sc-408930-ACT-2 from Santa Cruz Biotechnology
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CdGAP Lentiviral Activation Particles (h) - sc-408930-LAC from Santa Cruz Biotechnology
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CdGAP Lentiviral Activation Particles (h2) - sc-408930-LAC-2 from Santa Cruz Biotechnology
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CdGAP siRNA (h) - sc-78231 from Santa Cruz Biotechnology
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CdGAP shRNA Plasmid (h) - sc-78231-SH from Santa Cruz Biotechnology
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CdGAP shRNA (h) Lentiviral Particles - sc-78231-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU104301 from Sigma-Aldrich
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MISSION® esiRNA - EHU102631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3425 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3425 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09262 from Sigma-Aldrich
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ARHGAP31 siRNA (Human) - CRJ1500 from Cohesion Biosciences
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ARHGAP31 - MBS8207229 from MyBioSource
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shRNA set against Human ARHGAP31 (NM_020754.2) - SHH239502 from Creative biogene
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Human ARHGAP31 siRNA - orb272001 from Biorbyt
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ARHGAP31 shRNA Plasmid (Human) - CHJ1500 from Cohesion Biosciences
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