CDHR2

Gene Symbol CDHR2
Entrez Gene 54825
Alt Symbol PCDH24, PCLKC
Species Human
Gene Type protein-coding
Description cadherin-related family member 2
Other Description protocadherin 24|protocadherin-24
Swissprots A6NC80 Q9NXP8 A1L3U4 Q9BYE9
Accessions EAW85066 EAW85067 EAW85068 EAW85069 Q9BYE9 AA130780 AB047004 BAB40777 AK000131 BAA90962 AK000390 AK225217 AK315055 BAG37531 BC130282 AAI30283 BP271197 BX478954 XM_011534584 XP_011532886 NM_001171976 NP_001165447 NM_017675 NP_060145
Function Role in contact inhibition at the lateral surface of epithelial cells. {ECO:0000269|PubMed:12117771}.
Subcellular Location Apical cell membrane {ECO:0000269|PubMed:12117771}; Single-pass type I membrane protein {ECO:0000269|PubMed:12117771}. Cell junction {ECO:0000269|PubMed:12117771}. Note=Present at the cell junctions and the apical surface of cells. Colocalizes with actin at the microvilli-like structures which protrude from the apical surface.
Tissue Specificity Highly expressed in liver, kidney and colon. Moderately expressed in small intestine. Down-regulated in a number of liver and colon cancers. {ECO:0000269|PubMed:12117771, ECO:0000269|PubMed:15534908}.

PC-LKC (T-14) - sc-163207 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PC-LKC (V-14) - sc-163208 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PCLKC antibody - ab57440 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57440 PCLKC antibody at 1ug/ml.

PCLKC Antibody - NBP1-92246 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PCLKC Antibody [NBP1-92246] - Staining of human kidney shows moderate to strong membranous positivity in cells in tubules.

PCLKC Antibody - NBP1-92247 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: PCLKC Antibody [NBP1-92247] - Staining of human kidney shows strong membranous positivity in proximal tubules.

PCLKC Antibody - H00054825-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

PCLKC Antibody (1D2) - H00054825-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D2

PCLKC Polyclonal Antibody - bs-13729R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13729R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13729R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13729R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13729R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, Cy3 Conjugated - bs-13729R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, Cy5 Conjugated - bs-13729R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, Cy5.5 Conjugated - bs-13729R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, Cy7 Conjugated - bs-13729R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, FITC Conjugated - bs-13729R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, Biotin Conjugated - bs-13729R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PCLKC Polyclonal Antibody, HRP Conjugated - bs-13729R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-PCLKC antibody produced in mouse - WH0054825M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D2
<B>Immunoblotting</B><BR/>Monoclonal Anti-PCLKC, <B>Cat. No. WH0054825M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~38.1 kDa using immunogen protein lysate.

Anti-CDHR2 antibody produced in rabbit - HPA012569 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PCDH24: <B>Cat. No. HPA012569</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney shows strong membranous positivity in cells of tubules.

Anti-CDHR2 antibody produced in rabbit - HPA017053 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PCDH24: <B>Cat. No. HPA017053</B>: Immunohistochemical staining of human kidney shows strong membranous positivity in proximal tubules.

PCLKC antibody - H00054825-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

PCLKC antibody - H00054825-M01 from Acris Antibodies

Prices $360.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D2

PCLKC, Monoclonal Antibody - MBS6011953 from MyBioSource

Prices $580.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D2
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