| Gene Symbol |
CDHR2
|
| Entrez Gene |
54825
|
| Alt Symbol |
PCDH24, PCLKC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cadherin-related family member 2
|
| Other Description |
protocadherin 24|protocadherin-24
|
| Swissprots |
A6NC80 Q9NXP8 A1L3U4 Q9BYE9
|
| Accessions |
EAW85066 EAW85067 EAW85068 EAW85069 Q9BYE9 AA130780 AB047004 BAB40777 AK000131 BAA90962 AK000390 AK225217 AK315055 BAG37531 BC130282 AAI30283 BP271197 BX478954 XM_011534584 XP_011532886 NM_001171976 NP_001165447 NM_017675 NP_060145
|
| Function |
Role in contact inhibition at the lateral surface of epithelial cells. {ECO:0000269|PubMed:12117771}.
|
| Subcellular Location |
Apical cell membrane {ECO:0000269|PubMed:12117771}; Single-pass type I membrane protein {ECO:0000269|PubMed:12117771}. Cell junction {ECO:0000269|PubMed:12117771}. Note=Present at the cell junctions and the apical surface of cells. Colocalizes with actin at the microvilli-like structures which protrude from the apical surface.
|
| Tissue Specificity |
Highly expressed in liver, kidney and colon. Moderately expressed in small intestine. Down-regulated in a number of liver and colon cancers. {ECO:0000269|PubMed:12117771, ECO:0000269|PubMed:15534908}.
|