| Gene Symbol | MED4 |
|---|---|
| Entrez Gene | 29079 |
| Alt Symbol | ARC36, DRIP36, HSPC126, TRAP36, VDRIP |
| Species | Human |
| Gene Type | protein-coding |
| Description | mediator complex subunit 4 |
| Other Description | TRAP/SMCC/PC2 subunit p36|activator-recruited cofactor 36 kDa component|mediator of RNA polymerase II transcription subunit 4|mediator, 34-kD subunit, homolog|vitamin D receptor-interacting protein, 36-kD|vitamin D3 receptor-interacting protein complex 36 kDa component |
| Swissprots | Q9BS95 Q9NPJ6 Q6IA79 Q5T912 Q53GB4 Q53H68 Q9NYR5 Q6FHC4 B4DX67 |
| Accessions | EAX08783 EAX08784 EAX08785 EAX08786 Q9NPJ6 AF161475 AAF29090 AF230381 AAF37289 AF300618 AAG22542 AI613470 AK001934 BAA91987 AK222713 BAD96433 AK223017 BAD96737 AK301835 BAG63279 BC005189 AAH05189 BP309440 CR457276 CAG33557 CR541830 CAG46629 DQ893076 ABM84002 DQ896333 ABM87332 HG518167 CDI06890 NM_001270629 NP_001257558 NM_014166 NP_054885 |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Subcellular Location | Nucleus. |