Gene Symbol |
ASAP3
|
Entrez Gene |
55616
|
Alt Symbol |
ACAP4, CENTB6, DDEFL1, UPLC1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
|
Other Description |
ARF6 GTPase-activating protein|ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1|arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3|centaurin, beta 6|development and differentiation enhancing factor-like 1|development and differentiation-enhancing factor-like 1|protein up-regulated in liver cancer 1|up-regulated in liver cancer 1 (UPLC1)
|
Swissprots |
Q9NXK2 Q86UY1 B3KRW0 Q6P9F4 Q8TDY4 B4DHH4
|
Accessions |
EAW95050 EAW95051 EAW95052 EAW95053 Q8TDY4 AB056749 BAB85677 AK000206 BAA91008 AK000253 BAA91033 AK074319 AK092291 BAG52522 AK295100 BAG58136 AK299359 BAG61354 BC023519 AAH23519 BC052305 AAH52305 BC060786 AAH60786 XM_011541754 XP_011540056 XM_011541755 XP_011540057 XM_011541756 XP_011540058 XM_011541757 XP_011540059 XM_011541758 XP_011540060 NM_001143778 NP_001137250 NM_017707 NP_060177
|
Function |
Promotes cell proliferation. {ECO:0000269|PubMed:14654939}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:14654939}.
|
Tissue Specificity |
Highly expressed in primary hepatocarcinoma. Detected in lung, liver and blood leukocytes. {ECO:0000269|PubMed:14654939}.
|
Top Pathways |
Fc gamma R-mediated phagocytosis, Endocytosis
|