Gene Symbol | ASAP3 |
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Entrez Gene | 55616 |
Alt Symbol | ACAP4, CENTB6, DDEFL1, UPLC1 |
Species | Human |
Gene Type | protein-coding |
Description | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
Other Description | ARF6 GTPase-activating protein|ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 1|arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3|centaurin, beta 6|development and differentiation enhancing factor-like 1|development and differentiation-enhancing factor-like 1|protein up-regulated in liver cancer 1|up-regulated in liver cancer 1 (UPLC1) |
Swissprots | Q9NXK2 Q86UY1 B3KRW0 Q6P9F4 Q8TDY4 B4DHH4 |
Accessions | EAW95050 EAW95051 EAW95052 EAW95053 Q8TDY4 AB056749 BAB85677 AK000206 BAA91008 AK000253 BAA91033 AK074319 AK092291 BAG52522 AK295100 BAG58136 AK299359 BAG61354 BC023519 AAH23519 BC052305 AAH52305 BC060786 AAH60786 XM_011541754 XP_011540056 XM_011541755 XP_011540057 XM_011541756 XP_011540058 XM_011541757 XP_011540059 XM_011541758 XP_011540060 NM_001143778 NP_001137250 NM_017707 NP_060177 |
Function | Promotes cell proliferation. {ECO:0000269|PubMed:14654939}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:14654939}. |
Tissue Specificity | Highly expressed in primary hepatocarcinoma. Detected in lung, liver and blood leukocytes. {ECO:0000269|PubMed:14654939}. |
Top Pathways | Fc gamma R-mediated phagocytosis, Endocytosis |
DDEFL1 CRISPR/Cas9 KO Plasmid (h) - sc-412555 from Santa Cruz Biotechnology
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DDEFL1 HDR Plasmid (h) - sc-412555-HDR from Santa Cruz Biotechnology
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DDEFL1 Double Nickase Plasmid (h) - sc-412555-NIC from Santa Cruz Biotechnology
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DDEFL1 Double Nickase Plasmid (h2) - sc-412555-NIC-2 from Santa Cruz Biotechnology
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DDEFL1 CRISPR Activation Plasmid (h) - sc-412555-ACT from Santa Cruz Biotechnology
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DDEFL1 CRISPR Activation Plasmid (h2) - sc-412555-ACT-2 from Santa Cruz Biotechnology
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DDEFL1 Lentiviral Activation Particles (h) - sc-412555-LAC from Santa Cruz Biotechnology
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DDEFL1 Lentiviral Activation Particles (h2) - sc-412555-LAC-2 from Santa Cruz Biotechnology
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DDEFL1 siRNA (h) - sc-88264 from Santa Cruz Biotechnology
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DDEFL1 shRNA Plasmid (h) - sc-88264-SH from Santa Cruz Biotechnology
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DDEFL1 shRNA (h) Lentiviral Particles - sc-88264-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU062961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3565 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3565 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09057 from Sigma-Aldrich
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ASAP3 siRNA (Human) - CRJ0776 from Cohesion Biosciences
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ASAP3 - MBS8231546 from MyBioSource
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shRNA set against Human ASAP3 (NM_017707.3) - SHH241118 from Creative biogene
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ASAP3 shRNA Plasmid (Human) - CHJ0776 from Cohesion Biosciences
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ASAP3 miRNA 3'UTR clone - MiUTR3H-13659 from Creative biogene
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ASAP3 miRNA 3'UTR clone - MiUTR3H-13660 from Creative biogene
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