Gene Symbol | FNIP2 |
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Entrez Gene | 57600 |
Alt Symbol | FNIPL, MAPO1 |
Species | Human |
Gene Type | protein-coding |
Description | folliculin interacting protein 2 |
Other Description | FNIP1-like protein|O6-methylguanine-induced apoptosis 1 protein|folliculin-interacting protein 2 |
Swissprots | Q05DC3 Q9H994 Q96I31 Q9P278 |
Accessions | EAX04852 Q9P278 AB040883 BAA95974 AK022968 BAB14338 AK057981 AL713802 BC007861 AAH07861 BC016638 AAH16638 BC030251 BC047069 BC166693 AAI66693 BU753084 DB482145 XM_005263156 XP_005263213 XM_005263158 XP_005263215 XM_005263159 XP_005263216 XM_005263160 XP_005263217 XM_011532154 XP_011530456 XM_011532155 XP_011530457 XM_011532156 XP_011530458 NM_020840 NP_065891 |
Function | May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. {ECO:0000250, ECO:0000269|PubMed:18403135, ECO:0000269|PubMed:18663353}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18403135, ECO:0000269|PubMed:18663353, ECO:0000269|PubMed:19137017}. Note=Colocalizes with FLCN in the cytoplasm. |
Tissue Specificity | Widely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenta and pancreas. Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue. Higher levels detected in oncocytoma than in normal kidney. {ECO:0000269|PubMed:18403135, ECO:0000269|PubMed:18663353}. |
FNIP2 (P-14) - sc-241462 from Santa Cruz Biotechnology
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FNIP2 (S-20) - sc-241461 from Santa Cruz Biotechnology
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Anti-FNIP2 antibody - ab106611 from Abcam
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Anti-FNIP2 antibody - ab118609 from Abcam
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Anti-FNIP2 antibody - ab118613 from Abcam
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Anti-FNIP2 antibody - ab106605 from Abcam
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Anti-FNIP2 antibody - ab107380 from Abcam
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Anti-FNIP2 Antibody (aa776-804, AP) - LS-C235336 from LifeSpan Bioscience
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Anti-FNIP2 Antibody (aa776-804, APC) - LS-C235337 from LifeSpan Bioscience
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Anti-FNIP2 Antibody (aa776-804, Biotin) - LS-C235338 from LifeSpan Bioscience
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Anti-FNIP2 Antibody (aa776-804, FITC) - LS-C235339 from LifeSpan Bioscience
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Anti-FNIP2 Antibody (aa776-804, PE) - LS-C235340 from LifeSpan Bioscience
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Anti-FNIP2 Antibody (aa776-804, Azide-free, HRP) - LS-C248999 from LifeSpan Bioscience
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Anti-FNIP2 Antibody (aa783-812) - LS-C321416 from LifeSpan Bioscience
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Anti-FNIP2 Antibody (aa776-804) - LS-C166200 from LifeSpan Bioscience
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Anti-FNIP2 Antibody (N-Terminus) IHC-plus⢠- LS-B4600 from LifeSpan Bioscience
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Anti-FNIP2 Antibody (C-Terminus) IHC-plus⢠- LS-B4598 from LifeSpan Bioscience
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FNIP2 Antibody - NBP1-93724 from Novus Biologicals
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FNIP2 Polyclonal Antibody - bs-13194R from Bioss
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Rabbit Anti-FNIP2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13194R-A350 from Bioss
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Rabbit Anti-FNIP2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13194R-A488 from Bioss
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Rabbit Anti-FNIP2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13194R-A555 from Bioss
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Rabbit Anti-FNIP2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13194R-A647 from Bioss
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Rabbit Anti-FNIP2 Polyclonal Antibody, Cy5 Conjugated - bs-13194R-Cy5 from Bioss
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Rabbit Anti-FNIP2 Polyclonal Antibody, Cy5.5 Conjugated - bs-13194R-Cy5.5 from Bioss
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