FNIP2

Gene Symbol FNIP2
Entrez Gene 57600
Alt Symbol FNIPL, MAPO1
Species Human
Gene Type protein-coding
Description folliculin interacting protein 2
Other Description FNIP1-like protein|O6-methylguanine-induced apoptosis 1 protein|folliculin-interacting protein 2
Swissprots Q05DC3 Q9H994 Q96I31 Q9P278
Accessions EAX04852 Q9P278 AB040883 BAA95974 AK022968 BAB14338 AK057981 AL713802 BC007861 AAH07861 BC016638 AAH16638 BC030251 BC047069 BC166693 AAI66693 BU753084 DB482145 XM_005263156 XP_005263213 XM_005263158 XP_005263215 XM_005263159 XP_005263216 XM_005263160 XP_005263217 XM_011532154 XP_011530456 XM_011532155 XP_011530457 XM_011532156 XP_011530458 NM_020840 NP_065891
Function May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. {ECO:0000250, ECO:0000269|PubMed:18403135, ECO:0000269|PubMed:18663353}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18403135, ECO:0000269|PubMed:18663353, ECO:0000269|PubMed:19137017}. Note=Colocalizes with FLCN in the cytoplasm.
Tissue Specificity Widely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenta and pancreas. Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue. Higher levels detected in oncocytoma than in normal kidney. {ECO:0000269|PubMed:18403135, ECO:0000269|PubMed:18663353}.

FNIP2 CRISPR/Cas9 KO Plasmid (h) - sc-409140 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNIP2 HDR Plasmid (h) - sc-409140-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNIP2 Double Nickase Plasmid (h) - sc-409140-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNIP2 Double Nickase Plasmid (h2) - sc-409140-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNIP2 CRISPR Activation Plasmid (h) - sc-409140-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNIP2 CRISPR Activation Plasmid (h2) - sc-409140-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNIP2 Lentiviral Activation Particles (h) - sc-409140-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FNIP2 Lentiviral Activation Particles (h2) - sc-409140-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MISSION® esiRNA - EHU054551 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8862 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8862 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

FNIP2 siRNA (Human) - CRJ1572 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FNIP2 - MBS8214718 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FNIP2 (NM_020840.1) - SHH296213 from Creative biogene

Category siRNA
Species Reactivities Human

FNIP2 shRNA Plasmid (Human) - CHJ1572 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FNIP2 miRNA 3'UTR clone - MiUTR1H-05264 from Creative biogene

Species Reactivities Human
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