| Gene Symbol |
TCEA3
|
| Entrez Gene |
6920
|
| Alt Symbol |
TFIIS, TFIIS.H
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transcription elongation factor A (SII), 3
|
| Other Description |
rhabdomyosarcoma antigen MU-RMS-40.22|transcription elongation factor A protein 3|transcription elongation factor S-II protein 3|transcription elongation factor TFIIS.h
|
| Swissprots |
A8K2K7 Q5DR83 O75764
|
| Accessions |
EAW95048 EAW95049 O75764 AA873235 AJ223473 CAA11393 AK027024 AK290272 BAF82961 AK300707 BAG62386 AK310039 AY540752 AAT44402 BC041613 AAH41613 BE880226 BI835458 BQ003897 BQ949868 CU449151 EU446905 ABZ92434 HY070786 XM_006710864 XP_006710927 XM_011542053 XP_011540355 XM_011542054 XP_011540356 XM_011542055 XP_011540357 XM_011542056 XP_011540358 XM_011542057 XP_011540359 NM_003196 NP_003187
|
| Function |
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00649, ECO:0000255|PROSITE-ProRule:PRU00651}.
|
![Western Blot: TFIISH Overexpression Lysate (Native) [NBP2-08030] - TFIISH Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TCEA3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5221_TFIISH-Overexpression-Lysate-(Native)-Western-Blot-NBP2-08030-img0002.jpg)