Gene Symbol | TCEA3 |
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Entrez Gene | 6920 |
Alt Symbol | TFIIS, TFIIS.H |
Species | Human |
Gene Type | protein-coding |
Description | transcription elongation factor A (SII), 3 |
Other Description | rhabdomyosarcoma antigen MU-RMS-40.22|transcription elongation factor A protein 3|transcription elongation factor S-II protein 3|transcription elongation factor TFIIS.h |
Swissprots | A8K2K7 Q5DR83 O75764 |
Accessions | EAW95048 EAW95049 O75764 AA873235 AJ223473 CAA11393 AK027024 AK290272 BAF82961 AK300707 BAG62386 AK310039 AY540752 AAT44402 BC041613 AAH41613 BE880226 BI835458 BQ003897 BQ949868 CU449151 EU446905 ABZ92434 HY070786 XM_006710864 XP_006710927 XM_011542053 XP_011540355 XM_011542054 XP_011540356 XM_011542055 XP_011540357 XM_011542056 XP_011540358 XM_011542057 XP_011540359 NM_003196 NP_003187 |
Function | Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00649, ECO:0000255|PROSITE-ProRule:PRU00651}. |
TCEA3 CRISPR/Cas9 KO Plasmid (h) - sc-408517 from Santa Cruz Biotechnology
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TCEA3 HDR Plasmid (h) - sc-408517-HDR from Santa Cruz Biotechnology
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TCEA3 Double Nickase Plasmid (h) - sc-408517-NIC from Santa Cruz Biotechnology
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TCEA3 Double Nickase Plasmid (h2) - sc-408517-NIC-2 from Santa Cruz Biotechnology
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TCEA3 CRISPR Activation Plasmid (h) - sc-408517-ACT from Santa Cruz Biotechnology
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TCEA3 CRISPR Activation Plasmid (h2) - sc-408517-ACT-2 from Santa Cruz Biotechnology
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TCEA3 Lentiviral Activation Particles (h) - sc-408517-LAC from Santa Cruz Biotechnology
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TCEA3 Lentiviral Activation Particles (h2) - sc-408517-LAC-2 from Santa Cruz Biotechnology
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TCEA3 siRNA (h) - sc-63111 from Santa Cruz Biotechnology
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TCEA3 shRNA Plasmid (h) - sc-63111-SH from Santa Cruz Biotechnology
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TCEA3 shRNA (h) Lentiviral Particles - sc-63111-V from Santa Cruz Biotechnology
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TFIISH RNAi - H00006920-R01 from Novus Biologicals
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MISSION® esiRNA - EHU141971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21121 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03652 from Sigma-Aldrich
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TCEA3 siRNA (Human) - CRH4743 from Cohesion Biosciences
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TCEA3 - MBS8225220 from MyBioSource
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shRNA set against Human TCEA3 (NM_003196.1) - SHH424572 from Creative biogene
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shRNA set against Human TCEA3(NM_003196.1) - SHL061156 from Creative biogene
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Human TCEA3 siRNA - orb265245 from Biorbyt
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TCEA3 shRNA Plasmid (Human) - CHH4743 from Cohesion Biosciences
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TCEA3 miRNA 3'UTR clone - MiUTR1H-10256 from Creative biogene
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