| Gene Symbol |
FBXO17
|
| Entrez Gene |
115290
|
| Alt Symbol |
FBG4, FBX26, FBXO26, Fbx17
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
F-box protein 17
|
| Other Description |
F-box only protein 17|F-box only protein 26|F-box protein FBG4
|
| Swissprots |
Q96LQ4 Q96EF6
|
| Accessions |
EAW56853 EAW56854 EAW56855 Q96EF6 AF386743 AAL37625 AI050825 AK021860 AK057934 BAB71616 BC012385 AAH12385 BM711851 BX338290 CA429117 CF594009 DQ891329 ABM82255 DQ893357 ABM84283 DQ894512 ABM85438 DQ896676 ABM87675 NM_024907 NP_079183 NM_148169 NP_680474 NR_104026
|
| Function |
Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex- type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins.
|
| Tissue Specificity |
Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain. {ECO:0000269|PubMed:12383498}.
|