Gene Symbol | FBXO17 |
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Entrez Gene | 115290 |
Alt Symbol | FBG4, FBX26, FBXO26, Fbx17 |
Species | Human |
Gene Type | protein-coding |
Description | F-box protein 17 |
Other Description | F-box only protein 17|F-box only protein 26|F-box protein FBG4 |
Swissprots | Q96LQ4 Q96EF6 |
Accessions | EAW56853 EAW56854 EAW56855 Q96EF6 AF386743 AAL37625 AI050825 AK021860 AK057934 BAB71616 BC012385 AAH12385 BM711851 BX338290 CA429117 CF594009 DQ891329 ABM82255 DQ893357 ABM84283 DQ894512 ABM85438 DQ896676 ABM87675 NM_024907 NP_079183 NM_148169 NP_680474 NR_104026 |
Function | Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex- type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins. |
Tissue Specificity | Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain. {ECO:0000269|PubMed:12383498}. |
FBXO17 CRISPR/Cas9 KO Plasmid (h) - sc-406883 from Santa Cruz Biotechnology
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FBXO17 HDR Plasmid (h) - sc-406883-HDR from Santa Cruz Biotechnology
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FBXO17 Double Nickase Plasmid (h) - sc-406883-NIC from Santa Cruz Biotechnology
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FBXO17 Double Nickase Plasmid (h2) - sc-406883-NIC-2 from Santa Cruz Biotechnology
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FBXO17 CRISPR Activation Plasmid (h) - sc-406883-ACT from Santa Cruz Biotechnology
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FBXO17 CRISPR Activation Plasmid (h2) - sc-406883-ACT-2 from Santa Cruz Biotechnology
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FBXO17 Lentiviral Activation Particles (h) - sc-406883-LAC from Santa Cruz Biotechnology
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FBXO17 Lentiviral Activation Particles (h2) - sc-406883-LAC-2 from Santa Cruz Biotechnology
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FBXO17 siRNA (h) - sc-97555 from Santa Cruz Biotechnology
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FBXO17 shRNA Plasmid (h) - sc-97555-SH from Santa Cruz Biotechnology
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FBXO17 shRNA (h) Lentiviral Particles - sc-97555-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU023061 from Sigma-Aldrich
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MISSION® esiRNA - EHU129541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8536 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8536 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08628 from Sigma-Aldrich
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FBXO17 siRNA (Human) - CRJ4439 from Cohesion Biosciences
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FBXO17 - MBS8215045 from MyBioSource
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shRNA set against Human FBXO17(NM_148169.1) - SHH051725 from Creative biogene
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shRNA set against Human FBXO17(NM_024907.5) - SHH051761 from Creative biogene
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FBXO17 shRNA Plasmid (Human) - CHJ4439 from Cohesion Biosciences
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FBXO17 miRNA 3'UTR clone - MiUTR1H-03546 from Creative biogene
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FBXO17 miRNA 3'UTR clone - MiUTR1H-03547 from Creative biogene
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