LPCAT4

Gene Symbol LPCAT4
Entrez Gene 254531
Alt Symbol AGPAT7, AYTL3, LPAAT-eta, LPEAT2
Species Human
Gene Type protein-coding
Description lysophosphatidylcholine acyltransferase 4
Other Description 1-AGP acyltransferase 7|1-AGPAT 7|1-acylglycerol-3-phosphate O-acyltransferase 7 (lysophosphatidic acid acyltransferase, eta)|1-acylglycerophosphocholine O-acyltransferase|1-acylglycerophosphoserine O-acyltransferase|1-alkenylglycerophosphoethanolamine O-acyltransferase|1-alkylglycerophosphocholine O-acetyltransferase|PLSC domain containing protein|acyl-CoA:lysophosphatidylethanolamine acyltransferase 2|acyltransferase like 3|acyltransferase-like 3|lysophosphatidylethanolamine acyltransferase 2|lysophospholipid acyltransferase LPCAT4|plasmalogen synthase
Swissprots Q7Z4P4 A8K2K8 Q8IUL7 O43412 Q8TB38 Q643R3
Accessions EAW92306 EAW92307 EAW92308 Q643R3 AF007155 AAC19156 AF529233 AAP97722 AF542964 AAN33178 AK001119 AK290273 BAF82962 AK308910 AL832237 AY734233 AAU34184 BC024892 AAH24892 BC028209 BC048430 BC092463 AAH92463 BC144236 AAI44237 T29943 XM_006720454 XP_006720517 XM_011521422 XP_011519724 XR_243087 XR_243088 XR_931784 NM_153613 NP_705841
Function Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1- alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl- phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors. {ECO:0000269|PubMed:18458083}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:16243729, ECO:0000269|PubMed:18458083}; Multi- pass membrane protein {ECO:0000269|PubMed:16243729, ECO:0000269|PubMed:18458083}.
Tissue Specificity Widely expressed with predominant level in brain. {ECO:0000269|PubMed:16243729, ECO:0000269|PubMed:18458083}.
Top Pathways Ether lipid metabolism, Glycerophospholipid metabolism

Anti-AGPAT7 antibody - ab199181 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AGPAT7 antibody (ab199181) at 1/200 dilution + Human testis tissue lysate at 40 µgdeveloped using the ECL technique

Anti-AGPAT7 antibody - ab72726 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-AGPAT7 antibody (ab72726) at 1/500 dilutionLane 1 : AGPAT7 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

AGPAT7 Antibody - NBP1-90210 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AGPAT7 Antibody - H00254531-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: AGPAT7 Antibody [H00254531-B01] - analysis of AGPAT7 expression in transfected 293T cell line by AGPAT7 MaxPab polyclonal antibody (B01). Lane 1: AGPAT7 transfected lysate (57.20 KDa). Lane 2: Non-transfected lysate.

Anti-LPCAT4 antibody produced in rabbit - HPA030719 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-LPCAT4: <B>Cat. No. HPA030719</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic staining and nucleolar positivity in tubular cells.

Anti-LPCAT4 (4-15) antibody produced in rabbit - SAB1103313 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human LPCAT4 was separated on SDS-PAGE, blotted with Anti-LPCAT4 (4-15) (<B>Cat. No. SAB1103313</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + LPCAT4 immunizing peptide (human, 4-15)

Anti-LPCAT4 (486-500) antibody produced in rabbit - SAB1103314 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human LPCAT4 was separated on SDS-PAGE, blotted with Anti-LPCAT4 (486-500) (<B>Cat. No. SAB1103314</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

LPCAT1 antibody, C-term - GTX80419 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-PCAT1 antibody, C-term used in Flow cytometry/FACS. GTX80419

LPCAT4 antibody - 70R-18300 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

AGPAT7 antibody - 17905-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
HepG2 cells were subjected to SDS PAGE followed by western blot with 17905-1-AP(LPCAT4 antibody) at dilution of 1:500

AGPAT7 antibody - H00254531-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of LPCAT4 expression in transfected 293T cell line (H00254531-T01) by LPCAT4 MaxPab polyclonal antibody.Lane 1: AGPAT7

LPCAT4 antibody - 17905-1-AP from Proteintech Group

Prices $279.00
Sizes con: 27 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse brain tissue were subjected to SDS PAGE followed by western blot with 17905-1-AP(LPCAT4 antibody) at dilution of 1:500

lysophosphatidylcholine acyltransferase 4 , Polyclonal Antibody - MBS711981 from MyBioSource

Prices $230.00, $500.00
Sizes 50 µl, 150 µl
Host Rabbit
Clonality Polyclonal

LPCAT4 Antibody - 37091 from Signalway Antibody

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Gel: 8%SDS-PAGE Lysates (from left to right): Human testis tissue Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 8 minutes

LPCAT4, Polyclonal Antibody - MBS2526830 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

LPCAT4, Polyclonal Antibody - MBS2520468 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

LPCAT4 Polyclonal Antibody - ESAP12933 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Western blot analysis of Human testis tissue, using LPCAT4 Polyclonal Antibody at dilution of 1:200

LPCAT4 Polyclonal Antibody - ESAP16254 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Western blot analysis of PC3 cell and human testis tissue, using LPCAT4 Polyclonal Antibody at dilution of 1:400

Monoclonal Antibody to Lysophosphatidylcholine Acyltransferase 4 (LPCAT4) - MAG532Hu21 from Uscn Life Science Inc.

Host Mouse
Clonality Monoclonal

Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 4 (LPCAT4) - PAG532Hu01 from Uscn Life Science Inc.

Host Rabbit
Clonality Polyclonal

Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 4 (LPCAT4) - PAG532Mu01 from Uscn Life Science Inc.

Host Rabbit
Clonality Polyclonal

Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 4 (LPCAT4) - PAG532Mu02 from Uscn Life Science Inc.

Host Rabbit
Clonality Polyclonal

Anti-LPCAT4 monoclonal antibody - DCABH-12216 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

LPCAT4 Antibody - CSB-PA104701 from Cusabio

Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using at dilution 1/15.
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