DVL2

Gene Symbol DVL2
Entrez Gene 1856
Alt Symbol -
Species Human
Gene Type protein-coding
Description dishevelled segment polarity protein 2
Other Description dishevelled 2 (homologous to Drosophila dsh)|dishevelled, dsh homolog 2|segment polarity protein dishevelled homolog DVL-2
Swissprots Q53XM0 O14641 D3DTN3
Accessions EAW90244 EAW90245 O14641 AF006012 AAB65243 AK026019 AK297099 BAG59612 AK297285 BAG59756 AK304229 BAG65098 AK309771 AK312829 BC014844 AAH14844 BG716400 BT009822 AAP88824 CB994349 JF432818 ADZ16035 XM_005256502 XP_005256559 XM_006721469 XP_006721532 NM_004422 NP_004413
Function Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Note=Localizes at the cell membrane upon interaction with frizzled family members and promotes their internalization. Localizes to cytoplasmic puncta (By similarity). {ECO:0000250}.
Top Pathways Wnt signaling pathway, Notch signaling pathway, Basal cell carcinoma, Melanogenesis, HTLV-I infection

Dvl2 (30D2) Rabbit mAb - 3224 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 30D2
Western blot analysis of total cell lysates from various cell lines using Dvl2 (30D2) Rabbit mAb.

Dvl2 Antibody - 3216 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of total cell extracts from 293, COS, Mv 1 Lu, CHO and NICI-H1299 cells, using Dvl2 antibody.

Dvl-2 (C-2) - sc-271319 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dvl-2 (C-2): sc-271319. Western blot analysis of Dvl-2 expression in BT-20 (A) and HeLa (B) whole cell lysates.

Dvl-2 (10B5) - sc-8026 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dvl-2 (10B5): sc-8026. Western blot analysis of Dvl-2 expression in non-transfected: sc-110760 (A) and human Dvl-2 transfected: sc-111055 (B) 293 whole cell lysates.

Dvl-2 (D-11) - sc-393374 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dvl-2 (D-11): sc-393374. Western blot analysis of Dvl-2 expression in BT-20 (A), F9 (B) and NIH/3T3 (C) whole cell lysates.

Dvl-2 (D-6) - sc-390303 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dvl-2 (D-6): sc-390303. Western blot analysis of Dvl-2 expression in BT-20 whole cell lysate.

Dvl-2 (E-15) - sc-30872 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dvl-2 (E-15): sc-30872. Western blot analysis of Dvl-2 expression in non-transfected: sc-110760 (A) and human Dvl-2 transfected: sc-111055 (B) 293 whole cell lysates.

Dvl-2 (I-20) - sc-30871 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dvl-2 (I-20): sc-30871. Western blot analysis of Dvl-2 expression in non-transfected: sc-110760 (A) and human Dvl-2 transfected: sc-111055 (B) whole cell lysates.

Dvl-2 (F-13) - sc-30873 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Dvl-2 (H-75) - sc-13974 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Dvl-2 (H-75): sc-13974. Immunofluorescence staining of methanol-fixed SK-N-SH cells showing cytoplasmic localization.

Dvl-2 (N-19) - sc-7399 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dvl-2 (N-19): sc-7399. Western blot analysis of Dvl-2 expression in non-transfected: sc-110760 (A) and human Dvl-2 transfected: sc-111055 (B) 293 whole cell lysates.

Anti-Dishevelled 2 (phospho S143) antibody [EPNCIR145] - ab124933 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPNCIR145
All lanes : Anti-Dishevelled 2 (phospho S143) antibody [EPNCIR145] (ab124933) at 1/1000 dilutionLane 1 : F9 cell lysate untreatedLane 2 : F9 cell lysate treated with Alkaline PhosphataseLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti Rabbit IgG at 1/2000 dilution

Anti-Dishevelled 2 (phospho T224) antibody [EPNCIR146] - ab124941 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPNCIR146
All lanes : Anti-Dishevelled 2 (phospho T224) antibody [EPNCIR146] (ab124941) at 1/1000 dilutionLane 1 : HeLa cell lysate untreatedLane 2 : HeLa cell lysate treated with Calyculin ALysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti Rabbit IgG at 1/2000 dilution

Anti-Dishevelled 2 antibody - ab137528 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human lung squamous cell carcinoma tissue labelling Dishevelled 2 with ab137528 at 1/100 dilution.

Anti-Dishevelled 2 antibody - ab22616 from Abcam

Prices $378.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Dishevelled 2 antibody (ab22616) at 1/1000 dilutionLane 1 : THP1 (Human acute monocytic leukemia cell line) Whole Cell Lysate Lane 2 : Colon tissue lysate (Human) Tissue Lysate - adult normal tissue (ab30051)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Anti-Dishevelled 2 antibody - ab104438 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Dishevelled 2 antibody (ab104438) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-Dishevelled 2 antibody - ab22618 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab22618 staining Dishevelled 2 in murine rib cartilage by Immunohistochemistry (Frozen sections). Tissue was fixed with paraformaldehyde and permeabilized using 0.1% Triton. Samples were then blocked with 20% serum for 1 hour at 19°C followed by incubation with the primary antibody at a 1/100 dilution for 16 hours at 4°C. An Alexa Fluor® conjugated donkey anti-rabbit polyclonal was used as secondary antibody at a 1/200 dilution. Counterstain DAPI (blue).See Abreview

Anti-Dishevelled 2 antibody - ab168781 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Dishevelled 2 antibody (ab168781) at 1 µg/mlLane 1 : Dishevelled2 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-Dishevelled 2 antibody - ab123694 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Dishevelled 2 antibody (ab123694) at 1/100 dilution + CEM cell line lysates at 35 µg

Anti-DVL2 / Dishevelled 2 Antibody (aa173-222) - LS-C186642 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Thymus Tumor. DVL2 antibody dilution 1.0 ug/ml.

Anti-DVL2 / Dishevelled 2 Antibody (aa588-617) - LS-C167586 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DVL2 Antibody western blot of CEM cell line lysates (35 ug/lane). The DVL2 antibody detected the DVL2 protein (arrow).

Anti-DVL2 / Dishevelled 2 Antibody (aa588-617, Biotin) - LS-C256365 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DVL2 / Dishevelled 2 Antibody (aa588-617, FITC) - LS-C256366 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DVL2 / Dishevelled 2 Antibody (aa588-617, Azide-free, HRP) - LS-C256367 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DVL2 / Dishevelled 2 Antibody (aa588-617, PE) - LS-C256368 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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