Gene Symbol | Vegfc |
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Entrez Gene | 114111 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | vascular endothelial growth factor C |
Other Description | VEGF-C|VRP|flt4 ligand|flt4-L|vascular endothelial growth factor-related protein |
Swissprots | Q91ZE3 O35757 |
Accessions | EDL78943 EDL78944 EDL78945 O35757 AF010302 AAB63248 AY032729 AAK96009 NM_053653 NP_446105 |
Function | Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. |
Subcellular Location | Secreted. |
Tissue Specificity | Highly expressed in the lung, ovary, preputial gland and the adrenal gland. Expressed in the post-pubertal mammary glands. {ECO:0000269|PubMed:10878616, ECO:0000269|PubMed:11683876}. |
Top Pathways | Cytokine-cytokine receptor interaction, Focal adhesion, PI3K-Akt signaling pathway, Rap1 signaling pathway |
VEGF-C Antibody - NB110-61022 from Novus Biologicals
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VEGFC Antibody - abx103974 from Abbexa
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VEGFC Antibody - abx103976 from Abbexa
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VEGF-C / Flt4-L antibody - DP3507 from Acris Antibodies
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VEGF-C / Flt4-L antibody - DP3507S from Acris Antibodies
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VEGF-C / Flt4-L antibody - PAB13530 from Acris Antibodies
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Anti-Vascular Endothelial Growth Factor C (VEGFC) - 20-2349 from ARP American Research Products
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Anti-VEGFC polyclonal antibody - DPAB-DC425 from Creative Diagnostics
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VEGF-C, Polyclonal Antibody - MBS691160 from MyBioSource
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VEGF-C, Polyclonal Antibody - MBS692215 from MyBioSource
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VEGF-C, Polyclonal Antibody - MBS691452 from MyBioSource
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Monoclonal Antibody to Vascular Endothelial Growth Factor C (VEGFC) - MAA145Ra22 from Cloud-clone
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Polyclonal Antibody to Vascular Endothelial Growth Factor C (VEGFC) - PAA145Ra01 from Cloud-clone
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Biotin-Linked Antibody to Vascular Endothelial Growth Factor C (VEGFC) - PAA145Ra71 from Cloud-clone
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FITC-Linked Antibody to Vascular Endothelial Growth Factor C (VEGFC) - PAA145Ra81 from Cloud-clone
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Vascular Endothelial Growth Factor C (VEGFC) Monoclonal Antibody - CAU29205 from Biomatik
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Vascular Endothelial Growth Factor C (VEGFC) Polyclonal Antibody - CAU28458 from Biomatik
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VEGFC Antibody (OACD00167) - OACD00167 from Aviva Systems Biology
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