| Gene Symbol |
NOP58
|
| Entrez Gene |
51602
|
| Alt Symbol |
HSPC120, NOP5, NOP5/NOP58
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NOP58 ribonucleoprotein
|
| Other Description |
NOP58 ribonucleoprotein homolog|nucleolar protein 5|nucleolar protein 58|nucleolar protein NOP5/NOP58
|
| Swissprots |
Q9UFN3 Q53SA4 Q6PK08 Q9P036 Q9Y2X3
|
| Accessions |
AAY24145 EAW70308 Q9Y2X3 AF123534 AAD27610 AF161469 AAF29084 AF263608 AAF91394 AK023975 BAG51244 AK300844 BAG62495 AK307396 AL117554 CAB55989 BC001707 BC009306 AAH09306 BC018805 BC032592 AAH32592 DQ586402 DQ890868 ABM81794 EU176490 ABW03291 NM_015934 NP_057018
|
| Function |
Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs. {ECO:0000250, ECO:0000269|PubMed:15574333, ECO:0000269|PubMed:17636026, ECO:0000269|PubMed:19620283}.
|
| Subcellular Location |
Nucleus, nucleolus. Nucleus, nucleoplasm {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Ribosome biogenesis in eukaryotes
|
![Western Blot: NOP58 Overexpression Lysate (Adult Normal) [NBL1-13718] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NOP58.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6592_NOP58%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13718-img0002.jpg)