Gene Symbol | BMPR1B |
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Entrez Gene | 658 |
Alt Symbol | ALK-6, ALK6, CDw293 |
Species | Human |
Gene Type | protein-coding |
Description | bone morphogenetic protein receptor, type IB |
Other Description | BMP type-1B receptor|BMPR-1B|activin receptor-like kinase 6|bone morphogenetic protein receptor type-1B|serine/threonine receptor kinase |
Swissprots | O00238 B4DSV1 B2R953 P78366 |
Accessions | EAX06060 O00238 AK293008 BAF85697 AK299930 BAG61763 AK313642 BAG36400 AW299723 BC047773 AAH47773 BC069796 AAH69796 BC069803 AAH69803 D89675 BAA19765 U89326 AAC28131 XM_011532201 XP_011530503 XM_011532202 XP_011530504 NM_001203 NP_001194 NM_001256792 NP_001243721 NM_001256793 NP_001243722 NM_001256794 NP_001243723 |
Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells |
BMPR-IB (H-44) - sc-25455 from Santa Cruz Biotechnology
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BMPR-IB (N-17) - sc-5679 from Santa Cruz Biotechnology
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Anti-BMPR1B antibody - ab110955 from Abcam
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Anti-BMPR1B antibody - ab54907 from Abcam
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Anti-BMPR1B antibody - ab54909 from Abcam
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Anti-BMPR1B antibody [MM0055-3E12] - ab78417 from Abcam
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Anti-ALK-6 / BMPR1B Antibody - LS-C331823 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (N-Terminus, Biotin) - LS-C275573 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa17-32) - LS-C3034 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa27-150, clone 10K52, PE) - LS-C127074 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa14-503) - LS-C127075 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (Extracellular Domain, APC) - LS-C127076 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (Cytoplasmic Domain) - LS-C190052 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa133-160, AP) - LS-C252623 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa133-160, APC) - LS-C252625 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa133-160, Biotin) - LS-C252626 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa133-160, FITC) - LS-C252627 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa133-160, PE) - LS-C252629 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa134-162, AP) - LS-C252630 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa133-160, Azide-free, HRP) - LS-C252628 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa134-162, APC) - LS-C252631 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa1-30) - LS-C97659 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa2-31) - LS-C97661 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody - LS-C192704 from LifeSpan Bioscience
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Anti-ALK-6 / BMPR1B Antibody (aa134-162, Biotin) - LS-C252632 from LifeSpan Bioscience
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