BMPR1B

Gene Symbol BMPR1B
Entrez Gene 658
Alt Symbol ALK-6, ALK6, CDw293
Species Human
Gene Type protein-coding
Description bone morphogenetic protein receptor, type IB
Other Description BMP type-1B receptor|BMPR-1B|activin receptor-like kinase 6|bone morphogenetic protein receptor type-1B|serine/threonine receptor kinase
Swissprots O00238 B4DSV1 B2R953 P78366
Accessions EAX06060 O00238 AK293008 BAF85697 AK299930 BAG61763 AK313642 BAG36400 AW299723 BC047773 AAH47773 BC069796 AAH69796 BC069803 AAH69803 D89675 BAA19765 U89326 AAC28131 XM_011532201 XP_011530503 XM_011532202 XP_011530504 NM_001203 NP_001194 NM_001256792 NP_001243721 NM_001256793 NP_001243722 NM_001256794 NP_001243723
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells

Active human BMPR1B protein fragment - ab107949 from Abcam

Category Protein
Prices $302.00, $352.00, $1,845.00
Sizes 5 µg, 10 µg, 100 µg
Source Baculovirus infected sf9 cells
Species Human
Kinase Assay demonstrating specific activity of ab107949.

Active human BMPR1B protein fragment - ab157348 from Abcam

Category Protein
Prices $352.00
Sizes 50 µg
Source HEK 293 cells
Species Human
SDS-PAGE analysis of reduced ab157348 stained overnight with Coomassie Blue.

Human BMPR1B full length protein - ab131989 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
12.5% SDS-PAGE using ab131989 stained with Coomassie Blue.

Human BMPR1B protein fragment - ab152236 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab152236 stained with Coomassie Blue.

Human BMPR1B protein fragment - ab152237 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab152237 stained with Coomassie Blue.

Human BMPR1B protein fragment - ab202162 from Abcam

Category Protein
Prices $429.00
Sizes 20 µg
Source E. coli
Species Human
15% SDS-PAGE analysis of ab202162 (3µg).

ALK-6 / BMPR1B Antibody Blocking Peptide - LS-E1379 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK-6 / BMPR1B Antibody Blocking Peptide - LS-E4036 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK-6 / BMPR1B Antibody Blocking Peptide - LS-E6798 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK-6 / BMPR1B Antibody Blocking Peptide - LS-E6797 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALK-6 / BMPR1B Antibody Blocking Peptide - LS-E6799 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

BMPR-IB/ALK-6 Recombinant Protein - H00000658-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

BMPR-IB/ALK-6 Partial Recombinant Protein - H00000658-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

BMPR-IB/ALK-6 Partial Recombinant Protein - H00000658-Q03 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

BMPR-IB/ALK-6 Recombinant Protein - H00000658-G01 from Novus Biologicals

Category Protein
Prices $579.00
Sizes 10 µg
Species Human

BMPR-IB/ALK-6 Peptide - P0794 from Novus Biologicals

Category Peptide
Species Human

BMPR1B-Antibody-Center-Blocking-peptide - BP12034c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

BMPR1B-Antibody-N-term-D17-Blocking-Peptide - BP2005c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

BMPR1B-Antibody-C-term-Blocking-Peptide - BP2005b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

BMPR1B-Antibody-N-term-K15-Blocking-Peptide - BP2005a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human BMPR-IB/ALK-6 Fc Chimera, CF - 505-PR-100 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived

Human ALK-6 protein - orb138164 from Biorbyt

Category Protein
Prices $434.00, $646.00
Sizes 100 μg, 200 μg
Source Human Cells
Species Human
SDS-PAGE analysis of human ALK-6 protein

Human ALK-6 protein (GST Tag) - orb138163 from Biorbyt

Category Protein
Prices $323.00, $646.00
Sizes 20 μg, 100 μg
Source Baculovirus-Insect Cells
Species Human
SDS-PAGE analysis of human ALK-6 protein (GST Tag)

BMPR1B protein - 80R-4242 from Fitzgerald

Category Protein
Prices $295.00
Sizes 20 µg
Source E.coli

CDw293 / BMPR1B (14-126, His-tag) - AR51924PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 100 µg
Source E. coli
Species Human
CDw293 / BMPR1B
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