| Gene Symbol |
YWHAE
|
| Entrez Gene |
7531
|
| Alt Symbol |
14-3-3E, HEL2, KCIP-1, MDCR, MDS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
|
| Other Description |
14-3-3 epsilon|14-3-3 protein epsilon|epididymis luminal protein 2|mitochondrial import stimulation factor L subunit|protein kinase C inhibitor protein-1|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide|tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide
|
| Swissprots |
D3DTH5 B3KY71 P62258 Q7M4R4 Q4VJB6 Q53XZ5
|
| Accessions |
BAA32538 EAW90627 EAW90628 EAW90629 P62258 AK128785 BAG54733 AK295260 BAG58249 AK295997 BAG58772 AK296050 BAG58814 AK296555 BAG59178 AK316185 BAH14556 AK316201 BAH14572 AY883089 AAX68683 BC000179 AAH00179 BC001440 AAH01440 BM755263 BT007161 AAP35825 DC365395 EU176525 ABW03326 EU794581 ACJ13635 U20972 AAC50175 U28936 AAA75301 U43399 AAC50625 U43430 AAD00026 U54778 AAC50710 XM_005256784 XP_005256841 XM_006725298 XP_006725361 NM_006761 NP_006752 NR_024058
|
| Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Melanosome {ECO:0000269|PubMed:12042314, ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
|
| Top Pathways |
Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis, Viral carcinogenesis, PI3K-Akt signaling pathway
|
