| Gene Symbol |
ALG8
|
| Entrez Gene |
79053
|
| Alt Symbol |
CDG1H
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ALG8, alpha-1,3-glucosyltransferase
|
| Other Description |
HUSSY-02|asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)|asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase)|asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog|asparagine-linked glycosylation protein 8 homolog|dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase|dolichyl-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichol alpha- 1->3-glucosyltransferase|dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase|dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl-alpha-1,3-glucosyltransferase|probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
|
| Swissprots |
O60860 A6NDW6 Q9BVK2
|
| Accessions |
CCQ43710 EAW75048 EAW75049 EAW75050 EAW75051 Q9BVK2 AA375954 AJ224875 CAA12176 AK075184 AK075194 BAG52080 AK098614 AK125912 AK309050 BC001133 AAH01133 BC017892 DB362104 EU831448 ACE87135 XM_005274247 XP_005274304 XM_011545251 XP_011543553 XM_011545252 XP_011543554 XR_428923 XR_950044 XR_950045 NM_001007027 NP_001007028 NM_024079 NP_076984 NM_001007028
|
| Function |
Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
N-Glycan biosynthesis
|