ALG8
| Gene Symbol | ALG8 |
|---|---|
| Entrez Gene | 79053 |
| Alt Symbol | CDG1H |
| Species | Human |
| Gene Type | protein-coding |
| Description | ALG8, alpha-1,3-glucosyltransferase |
| Other Description | HUSSY-02|asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)|asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase)|asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog|asparagine-linked glycosylation protein 8 homolog|dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase|dolichyl-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichol alpha- 1->3-glucosyltransferase|dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase|dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl-alpha-1,3-glucosyltransferase|probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase |
| Swissprots | O60860 A6NDW6 Q9BVK2 |
| Accessions | CCQ43710 EAW75048 EAW75049 EAW75050 EAW75051 Q9BVK2 AA375954 AJ224875 CAA12176 AK075184 AK075194 BAG52080 AK098614 AK125912 AK309050 BC001133 AAH01133 BC017892 DB362104 EU831448 ACE87135 XM_005274247 XP_005274304 XM_011545251 XP_011543553 XM_011545252 XP_011543554 XR_428923 XR_950044 XR_950045 NM_001007027 NP_001007028 NM_024079 NP_076984 NM_001007028 |
| Function | Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity). {ECO:0000250}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | N-Glycan biosynthesis |
ALG8 CRISPR/Cas9 KO Plasmid (h) - sc-413121 from Santa Cruz Biotechnology
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ALG8 HDR Plasmid (h) - sc-413121-HDR from Santa Cruz Biotechnology
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ALG8 Double Nickase Plasmid (h) - sc-413121-NIC from Santa Cruz Biotechnology
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ALG8 Double Nickase Plasmid (h2) - sc-413121-NIC-2 from Santa Cruz Biotechnology
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ALG8 CRISPR Activation Plasmid (h) - sc-413121-ACT from Santa Cruz Biotechnology
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ALG8 CRISPR Activation Plasmid (h2) - sc-413121-ACT-2 from Santa Cruz Biotechnology
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ALG8 Lentiviral Activation Particles (h) - sc-413121-LAC from Santa Cruz Biotechnology
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ALG8 Lentiviral Activation Particles (h2) - sc-413121-LAC-2 from Santa Cruz Biotechnology
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ALG8 siRNA (h) - sc-96751 from Santa Cruz Biotechnology
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ALG8 shRNA Plasmid (h) - sc-96751-SH from Santa Cruz Biotechnology
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ALG8 shRNA (h) Lentiviral Particles - sc-96751-V from Santa Cruz Biotechnology
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ALG8 RNAi - H00079053-R01 from Novus Biologicals
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ALG8 RNAi - H00079053-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN3064 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3064 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02236 from Sigma-Aldrich
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ALG8 siRNA (Human) - CRJ2280 from Cohesion Biosciences
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ALG8 - MBS8216446 from MyBioSource
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shRNA set against Human ALG8 (NM_024079.4) - SHH235178 from Creative biogene
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shRNA set against Human ALG8(NM_024079.4) - SHG053835 from Creative biogene
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shRNA set against Human ALG8(NM_001007027.2) - SHG053853 from Creative biogene
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Human ALG8 siRNA - orb272781 from Biorbyt
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ALG8 shRNA Plasmid (Human) - CHJ2280 from Cohesion Biosciences
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ALG8 miRNA 3'UTR clone - MiUTR1H-00301 from Creative biogene
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ALG8 miRNA 3'UTR clone - MiUTR1H-00302 from Creative biogene
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