PCID2

Gene Symbol	PCID2
Entrez Gene	55795
Alt Symbol	F10
Species	Human
Gene Type	protein-coding
Description	PCI domain containing 2
Other Description	CSN12-like protein|PCI domain-containing protein 2
Swissprots	Q9HBZ7 Q3ZCX1 Q9NW44 Q9NUK6 Q5JVF3 Q9NVY1 Q5TC58 Q5TC57 Q9H7K1 Q9NWH3 A6NK09
Accessions	EAX09189 EAX09190 EAX09191 EAX09192 EAX09193 EAX09194 EAX09195 EAX09196 EAX09197 EAX09198 EAX09199 EAX09200 Q5JVF3 AA779868 AF183426 AAG09695 AI272719 AK000888 BAA91407 AK001185 BAA91542 AK001302 BAA91611 AK002167 BAA92118 AK023313 BAB14521 AK024478 BAB15768 AK098706 AK289462 BAF82151 AK309321 BC008975 AAH08975 BC016614 AAH16614 BC031246 AAH31246 BM932149 BP244753 DA058550 XM_005268324 XP_005268381 XM_005268325 XP_005268382 XM_011537510 XP_011535812 XM_011537511 XP_011535813 XM_011537512 XP_011535814 XM_011537513 XP_011535815 XM_011537514 XP_011535816 XM_011537515 XP_011535817 XM_011537516 XP_011535818 XM_011537517 XP_011535819 NM_001127202 NP_001120674 NM_001127203 NP_001120675 NM_001258212 NP_001245141 NM_001258213 NP_001245142 NM_018386 NP_060856
Function	Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export- competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop- associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2- depleted cells. {ECO:0000250, ECO:0000269|PubMed:22307388, ECO:0000269|PubMed:24896180}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Coagulation Factor X Colorimetric Assay Kit - KA0972 from Novus Biologicals Category Assay Kit Prices $659.00 Sizes 1 kit

Coagulation factor X, F10, Human, ELISA Kit - E0834h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Human F10 ELISA Kit - HF0025 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human F10(Coagulation Factor Ⅹ) ELISA Kit - E-EL-H0761 from Elabscience Category ELISA Kit Sensitivity 56.25 pg/mL Range 93.75—6000 pg/mL

Human F10 (Coagulation Factor X) CLIA Kit - E-CL-H0547 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

F10, ELISA Kit - MBS2511751 from MyBioSource Category ELISA Kit Prices $445.00 Sizes 96 -strip-wells Sensitivity 56.25pg/mL Range 93.75--6000pg/mL

PCI domain containing 2, ELISA Kit - MBS9316888 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Coagulation Factor X ELISA - E01F0018 from BlueGene Biotech Category ELISA Kit Sensitivity 1.0pg/mL

Human F10 (Coagulation Factor X) CLIA Kit - E-CL-H0547 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 56.25pg/mL Range 93.75-6000pg/mL

Human F10 ELISA Kit - abx576513 from Abbexa Category ELISA Kit Sensitivity 39.5 pg/ml Range 93.75 pg/ml - 6000 pg/ml

F10 - EKH2130 from Nordic BioSite Sensitivity 56.25pg/ml Range 93.75--6000pg/ml

Human F10 ELISA Kit - E009847 from Biobool Category ELISA Kit Sensitivity Typically less than 0.09ng/mL.

Human PCID2 ELISA Kit - E028394 from Biobool Category ELISA Kit

Human F10 ELISA Kit - EHF0025 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

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