| Gene Symbol |
TMEM5
|
| Entrez Gene |
10329
|
| Alt Symbol |
HP10481, MDDGA10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 5
|
| Other Description |
type II membrane protein
|
| Swissprots |
A8K017 Q6PKD6 Q9Y2B1
|
| Accessions |
EAW97120 EAW97121 Q9Y2B1 AB015633 BAA76500 AI458269 AK124211 AK289382 BAF82071 BC002596 AAH02596 BC013152 AAH13152 BM547839 BX647105 BX647419 DQ891077 ABM82003 DQ894259 ABM85185 XM_005268562 XP_005268619 XM_005268563 XP_005268620 XM_006719196 XP_006719259 NM_001278237 NP_001265166 NM_014254 NP_055069
|
| Function |
Involved in the biosynthesis of the phosphorylated O- mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N- acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. {ECO:0000269|PubMed:25279699}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:25279699}; Single-pass type II membrane protein {ECO:0000305}.
|
