Gene Symbol | TMEM5 |
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Entrez Gene | 10329 |
Alt Symbol | HP10481, MDDGA10 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 5 |
Other Description | type II membrane protein |
Swissprots | A8K017 Q6PKD6 Q9Y2B1 |
Accessions | EAW97120 EAW97121 Q9Y2B1 AB015633 BAA76500 AI458269 AK124211 AK289382 BAF82071 BC002596 AAH02596 BC013152 AAH13152 BM547839 BX647105 BX647419 DQ891077 ABM82003 DQ894259 ABM85185 XM_005268562 XP_005268619 XM_005268563 XP_005268620 XM_006719196 XP_006719259 NM_001278237 NP_001265166 NM_014254 NP_055069 |
Function | Involved in the biosynthesis of the phosphorylated O- mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N- acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. {ECO:0000269|PubMed:25279699}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000269|PubMed:25279699}; Single-pass type II membrane protein {ECO:0000305}. |
TMEM5 CRISPR/Cas9 KO Plasmid (h) - sc-411455 from Santa Cruz Biotechnology
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TMEM5 HDR Plasmid (h) - sc-411455-HDR from Santa Cruz Biotechnology
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TMEM5 Double Nickase Plasmid (h) - sc-411455-NIC from Santa Cruz Biotechnology
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TMEM5 Double Nickase Plasmid (h2) - sc-411455-NIC-2 from Santa Cruz Biotechnology
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TMEM5 CRISPR Activation Plasmid (h) - sc-411455-ACT from Santa Cruz Biotechnology
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TMEM5 CRISPR Activation Plasmid (h2) - sc-411455-ACT-2 from Santa Cruz Biotechnology
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TMEM5 Lentiviral Activation Particles (h) - sc-411455-LAC from Santa Cruz Biotechnology
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TMEM5 Lentiviral Activation Particles (h2) - sc-411455-LAC-2 from Santa Cruz Biotechnology
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TMEM5 siRNA (h) - sc-76692 from Santa Cruz Biotechnology
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TMEM5 shRNA Plasmid (h) - sc-76692-SH from Santa Cruz Biotechnology
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TMEM5 shRNA (h) Lentiviral Particles - sc-76692-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU130491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21636 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21636 from Sigma-Aldrich
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TMEM5 siRNA (Human) - CRH7002 from Cohesion Biosciences
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TMEM5 - MBS829774 from MyBioSource
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shRNA set against Human TMEM5 (NM_014254.1) - SHH430628 from Creative biogene
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shRNA set against Human TMEM5(NM_014254.1) - SHL079902 from Creative biogene
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TMEM5 shRNA Plasmid (Human) - CHH7002 from Cohesion Biosciences
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TMEM5 miRNA 3'UTR clone - MiUTR1H-10541 from Creative biogene
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