Gene Symbol |
Mterf4
|
Entrez Gene |
69821
|
Alt Symbol |
1810059A23Rik, 4933412H03Rik, Mterfd2
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
mitochondrial transcription termination factor 4
|
Other Description |
MTERF domain containing 2|mTERF domain-containing protein 2|transcription termination factor 4, mitochondrial
|
Swissprots |
Q99LQ0 Q8BVN4
|
Accessions |
EDL39965 EDL39966 Q8BVN4 AK007901 AK033043 AK077142 BAC36640 AK079098 BC002280 AAH02280 BC055877 AAH55877 BC064709 AAH64709 BY261356 XM_011248070 XP_011246372 NM_178051 NP_835152
|
Function |
Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S (By similarity). Targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit. {ECO:0000250, ECO:0000269|PubMed:21531335}.
|
Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:21531335}.
|
Tissue Specificity |
Widely expressed, with highest levels in liver, followed by testis, kidney and brain. {ECO:0000269|PubMed:21531335}.
|