Gene Symbol | Mterf4 |
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Entrez Gene | 69821 |
Alt Symbol | 1810059A23Rik, 4933412H03Rik, Mterfd2 |
Species | Mouse |
Gene Type | protein-coding |
Description | mitochondrial transcription termination factor 4 |
Other Description | MTERF domain containing 2|mTERF domain-containing protein 2|transcription termination factor 4, mitochondrial |
Swissprots | Q99LQ0 Q8BVN4 |
Accessions | EDL39965 EDL39966 Q8BVN4 AK007901 AK033043 AK077142 BAC36640 AK079098 BC002280 AAH02280 BC055877 AAH55877 BC064709 AAH64709 BY261356 XM_011248070 XP_011246372 NM_178051 NP_835152 |
Function | Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S (By similarity). Targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit. {ECO:0000250, ECO:0000269|PubMed:21531335}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:21531335}. |
Tissue Specificity | Widely expressed, with highest levels in liver, followed by testis, kidney and brain. {ECO:0000269|PubMed:21531335}. |
MTERFD2 CRISPR/Cas9 KO Plasmid (m) - sc-427547 from Santa Cruz Biotechnology
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MTERFD2 HDR Plasmid (m) - sc-427547-HDR from Santa Cruz Biotechnology
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MTERFD2 Double Nickase Plasmid (m) - sc-427547-NIC from Santa Cruz Biotechnology
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MTERFD2 Double Nickase Plasmid (m2) - sc-427547-NIC-2 from Santa Cruz Biotechnology
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MTERFD2 CRISPR Activation Plasmid (m) - sc-427547-ACT from Santa Cruz Biotechnology
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MTERFD2 CRISPR Activation Plasmid (m2) - sc-427547-ACT-2 from Santa Cruz Biotechnology
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MTERFD2 Lentiviral Activation Particles (m) - sc-427547-LAC from Santa Cruz Biotechnology
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MTERFD2 Lentiviral Activation Particles (m2) - sc-427547-LAC-2 from Santa Cruz Biotechnology
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MTERFD2 siRNA (m) - sc-149674 from Santa Cruz Biotechnology
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MTERFD2 shRNA Plasmid (m) - sc-149674-SH from Santa Cruz Biotechnology
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MTERFD2 shRNA (m) Lentiviral Particles - sc-149674-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN35931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND35931 from Sigma-Aldrich
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MTERFD2 siRNA (Mouse) - CRM8090 from Cohesion Biosciences
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shRNA set against Mouse MTERFD2 (NM_178051.3) - SHH346228 from Creative biogene
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shRNA set against Mouse Mterfd2(NM_178051.3) - SHH205777 from Creative biogene
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Mouse MTERFD2 siRNA - orb287566 from Biorbyt
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MTERFD2 shRNA Plasmid (Mouse) - CHM8090 from Cohesion Biosciences
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MTERFD2 miRNA 3'UTR clone - MiUTR1M-07368 from Creative biogene
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