CASP7

Gene Symbol	CASP7
Entrez Gene	840
Alt Symbol	CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Species	Human
Gene Type	protein-coding
Description	caspase 7, apoptosis-related cysteine peptidase
Other Description	ICE-like apoptotic protease 3|apoptotic protease MCH-3|caspase 7, apoptosis-related cysteine protease|caspase-7
Swissprots	Q5SVL0 Q53YD5 D3DRB8 B4DQU7 Q5SVL3 Q96BA0 B5BU45 P55210 Q13364
Accessions	CAV28504 EAW49494 EAW49495 EAW49496 EAW49497 EAW49498 P55210 AB451281 BAG70095 AB451413 BAG70227 AK223489 AK298964 BAG61059 AK300578 BAG62277 AK301437 BAG62964 AU130224 BC015799 AAH15799 BM976488 BP429646 BQ006259 BQ007179 BT006683 AAP35329 BX487250 BX647973 DC332144 DC364916 DC384804 DQ890614 ABM92231 DQ893769 ABM84695 EU831939 ACE87380 EU832034 ACE86696 U37448 AAC50303 U37449 AAC50304 U39613 AAC50346 U40281 AAC50352 U67206 AAF21460 U67320 AAC51153 XM_006718017 XP_006718080 XM_006718018 XP_006718081 XM_011540259 XP_011538561 XM_011540260 XP_011538562 NM_001227 NP_001218 NM_001267056 NP_001253985 NM_001267057 NP_001253986 NM_001267058 NP_001253987 NM_033338 NP_203124 NM_033339 NP_203125 NM_033340 NP_203126
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death.
Subcellular Location	Cytoplasm.
Tissue Specificity	Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Top Pathways	Apoptosis, Alzheimer's disease, Pertussis, Legionellosis, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CASP7 293T Cell Transient Overexpression Lysate(Denatured) - H00000840-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CASP7 overexpression lysate - LY409591 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CASP7 overexpression lysate - LY409592 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CASP7 overexpression lysate - LY409593 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CASP7 overexpression lysate - LY420060 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CASP7 overexpression lysate - LY429055 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CASP7 overexpression lysate - LY429870 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CASP7 293 Cell Lysate - 405019 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CASP7 293 Cell Lysate - 405020 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Caspase-7 Overexpression Lysate (Denatured) - H00000840-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Caspase-7 Overexpression Lysate (Native) - NBP2-05889 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Caspase-7 Overexpression Lysate (Native) - NBL1-08716 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

caspase-7 (h): 293 Lysate - sc-112228 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

caspase-7 (h): 293T Lysate - sc-176076 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

caspase-7 (h2): 293T Lysate - sc-176087 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

caspase-7 (h2): 293T Lysate - sc-177030 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CASP7 Over-expression Lysate Product - GWB-A00944 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

CASP7 Over-expression Lysate Product - GWB-8E34BA from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Caspase-7 Overexpression Lysate (Native) - NBP2-11334 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Caspase-7 Overexpression Lysate (Native) - NBP2-10963 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CASP7 knockout Cell lysate - LC810698 from Acris Antibodies Category Cell Lysate Prices $495.00 Sizes 100 µg

Panoply™ Human CASP7 Knockdown Stable Cell Line - CSC-DC002398 from Creative biogene Category Cell Line Species Human

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