| Gene Symbol |
NCLN
|
| Entrez Gene |
56926
|
| Alt Symbol |
NET59
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nicalin
|
| Other Description |
nicalin homolog (zebrefish)|nicastrin-like protein
|
| Swissprots |
Q96H48 Q6ZMB7 Q9BTX4 Q8TAT7 Q6FI60 D6W613 O75252 Q96IS7 Q9BQH9 Q969V3 Q9NPP2
|
| Accessions |
AAC27667 CAC16637 CAW38766 CAW54087 CBC04638 CBC26779 EAW69330 EAW69331 EAW69332 EAW69333 EAW69334 EAW69335 Q969V3 AK022309 AK125002 AK172848 BAD18812 AK314044 BAG36753 AL136567 CAB66502 AL365369 CAB96945 AM393010 CAL37888 BC003076 AAH03076 BC007275 AAH07275 BC008920 AAH08920 BC010064 AAH10064 BC013283 AAH13283 BC019091 AAH19091 BC025926 AAH25926 CR533566 CAG38597 XM_005259596 XP_005259653 NM_020170 NP_064555
|
| Function |
May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:15257293, ECO:0000269|PubMed:20538592}; Single-pass membrane protein {ECO:0000269|PubMed:15257293, ECO:0000269|PubMed:20538592}.
|
| Tissue Specificity |
Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart. {ECO:0000269|PubMed:15257293}.
|