Gene Symbol | VAPA |
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Entrez Gene | 9218 |
Alt Symbol | VAP-33, VAP-A, VAP33, hVAP-33 |
Species | Human |
Gene Type | protein-coding |
Description | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa |
Other Description | 33 kDa VAMP-associated protein|VAMP-A|VAMP-associated protein A|vesicle-associated membrane protein-associated protein A |
Swissprots | Q9P0L0 Q5U0E7 O75453 Q9UBZ2 D3DUI3 A6NDZ0 |
Accessions | EAX01590 EAX01591 EAX01592 Q9P0L0 AF044670 AAD09742 AF057358 AAC26508 AF086627 AAD13576 AF154847 AAF72105 AK024299 AK096868 AK123434 AK292948 BAF85637 AK315577 BAG37951 BC002992 AAH02992 BC033947 BC042860 BG488667 BG719406 BP209270 BT019618 AAV38424 XM_011525769 XP_011524071 NM_003574 NP_003565 NM_194434 NP_919415 |
Function | May play a role in vesicle trafficking. {ECO:0000269|PubMed:11511104, ECO:0000269|PubMed:19289470}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10523508, ECO:0000269|PubMed:19289470}; Single-pass type IV membrane protein {ECO:0000269|PubMed:10523508, ECO:0000269|PubMed:19289470}. Note=Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Tight junction |
VAP-A CRISPR/Cas9 KO Plasmid (h) - sc-403093 from Santa Cruz Biotechnology
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VAP-A HDR Plasmid (h) - sc-403093-HDR from Santa Cruz Biotechnology
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VAP-A Double Nickase Plasmid (h) - sc-403093-NIC from Santa Cruz Biotechnology
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VAP-A Double Nickase Plasmid (h2) - sc-403093-NIC-2 from Santa Cruz Biotechnology
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VAP-A CRISPR Activation Plasmid (h) - sc-403093-ACT from Santa Cruz Biotechnology
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VAP-A CRISPR Activation Plasmid (h2) - sc-403093-ACT-2 from Santa Cruz Biotechnology
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VAP-A Lentiviral Activation Particles (h) - sc-403093-LAC from Santa Cruz Biotechnology
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VAP-A Lentiviral Activation Particles (h2) - sc-403093-LAC-2 from Santa Cruz Biotechnology
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VAP-A siRNA (h) - sc-61768 from Santa Cruz Biotechnology
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VAP-A shRNA Plasmid (h) - sc-61768-SH from Santa Cruz Biotechnology
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VAP-A shRNA (h) Lentiviral Particles - sc-61768-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU082231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22638 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22638 from Sigma-Aldrich
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VAPA siRNA (Human) - CRH6102 from Cohesion Biosciences
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VAPA - MBS8202208 from MyBioSource
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shRNA set against Human VAPA (NM_194434.2) - SHH442236 from Creative biogene
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shRNA set against Human VAPA(NM_003574.5) - SHL121404 from Creative biogene
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shRNA set against Human VAPA(NM_194434.2) - SHL121422 from Creative biogene
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Human VAPA siRNA - orb266604 from Biorbyt
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VAPA shRNA Plasmid (Human) - CHH6102 from Cohesion Biosciences
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VAPA miRNA 3'UTR clone - MiUTR1H-11094 from Creative biogene
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VAPA miRNA 3'UTR clone - MiUTR1H-11095 from Creative biogene
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