Gene Symbol | NRIP1 |
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Entrez Gene | 8204 |
Alt Symbol | RIP140 |
Species | Human |
Gene Type | protein-coding |
Description | nuclear receptor interacting protein 1 |
Other Description | nuclear factor RIP140|nuclear receptor-interacting protein 1|receptor interacting protein 140|receptor-interacting protein 140 |
Swissprots | Q8IWE8 P48552 |
Accessions | AAF35255 AAF62185 CAB90396 CAD34981 EAX10047 P48552 AK123818 AK289786 BAF82475 BC040361 AAH40361 BE792046 DQ891180 ABM82106 DQ894362 ABM85288 HF584749 CCQ44046 HF584750 CCQ44047 X84373 CAA59108 XM_005261063 XP_005261120 XM_005261065 XP_005261122 XM_011529747 XP_011528049 XM_011529748 XP_011528050 XM_011529749 XP_011528051 XM_011529750 XP_011528052 XM_011529751 XP_011528053 XM_011529752 XP_011528054 NM_003489 NP_003480 |
Function | Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. {ECO:0000269|PubMed:10364267, ECO:0000269|PubMed:11509661, ECO:0000269|PubMed:11518808, ECO:0000269|PubMed:12554755, ECO:0000269|PubMed:15060175, ECO:0000269|PubMed:21628546, ECO:0000269|PubMed:7641693}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11266503, ECO:0000269|PubMed:12773562, ECO:0000269|PubMed:15060175, ECO:0000269|PubMed:7641693}. Note=Localized to discrete foci and redistributes to larger nuclear domains upon binding to ligand- bound NR3C1. |
RIP140 CRISPR/Cas9 KO Plasmid (h) - sc-401787 from Santa Cruz Biotechnology
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RIP140 HDR Plasmid (h) - sc-401787-HDR from Santa Cruz Biotechnology
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RIP140 Double Nickase Plasmid (h) - sc-401787-NIC from Santa Cruz Biotechnology
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RIP140 Double Nickase Plasmid (h2) - sc-401787-NIC-2 from Santa Cruz Biotechnology
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RIP140 CRISPR Activation Plasmid (h) - sc-401787-ACT from Santa Cruz Biotechnology
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RIP140 CRISPR Activation Plasmid (h2) - sc-401787-ACT-2 from Santa Cruz Biotechnology
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RIP140 Lentiviral Activation Particles (h) - sc-401787-LAC from Santa Cruz Biotechnology
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RIP140 Lentiviral Activation Particles (h2) - sc-401787-LAC-2 from Santa Cruz Biotechnology
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RIP140 siRNA (h) - sc-36428 from Santa Cruz Biotechnology
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RIP140 shRNA Plasmid (h) - sc-36428-SH from Santa Cruz Biotechnology
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RIP140 shRNA (h) Lentiviral Particles - sc-36428-V from Santa Cruz Biotechnology
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RIP140 RNAi - H00008204-R01 from Novus Biologicals
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MISSION® esiRNA - EHU009781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15513 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15513 from Sigma-Aldrich
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NRIP1 siRNA (Human) - CRH5396 from Cohesion Biosciences
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shRNA set against Human NRIP1 (NM_003489.3) - SHH355092 from Creative biogene
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Human NRIP1 siRNA - orb265898 from Biorbyt
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NRIP1 shRNA Plasmid (Human) - CHH5396 from Cohesion Biosciences
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NRIP1 miRNA 3'UTR clone - MiUTR4H-TG06130 from Creative biogene
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