NFIL3

Gene Symbol NFIL3
Entrez Gene 4783
Alt Symbol E4BP4, IL3BP1, NF-IL3A, NFIL3A
Species Human
Gene Type protein-coding
Description nuclear factor, interleukin 3 regulated
Other Description E4 promoter-binding protein 4|interleukin-3 promoter transcriptional activator|interleukin-3-binding protein 1|nuclear factor interleukin 3 regulated protein|nuclear factor interleukin-3-regulated protein|transcriptional activator NF-IL3A
Swissprots Q96HS0 B2R9Y8 Q6FGQ8 Q14211 Q16649
Accessions ABK15691 EAW62796 EAW62797 Q16649 AK313970 BAG36685 AW163045 BC008197 AAH08197 BQ937243 CR542049 CAG46846 DB256817 DQ891105 ABM82031 HM204564 ADK11690 HQ447282 ADQ31769 HY038941 S79880 AAB35410 U26173 AAA93067 X64318 CAA45597 NM_001289999 NP_001276928 NM_001290000 NP_001276929 NM_005384 NP_005375
Function Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity). Represses transcriptional activity of PER1 (By similarity). Represses transcriptional activity of PER2 via the B- site on the promoter (By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity). Protects pro-B cells from programmed cell death (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}.
Tissue Specificity Expressed in bladder stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and muscle. {ECO:0000269|PubMed:10942106}.

E4BP4/NFIL3 (D5K8O) Rabbit mAb - 14312 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5K8O
Western blot analysis of extracts from various cell lines using E4BP4/NFIL3 (D5K8O) Rabbit mAb.

E4BP4 (C-6) - sc-374451 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
E4BP4 (C-6): sc-374451. Western blot analysis of E4BP4 expression in non-transfected 293: sc-110760 (A), human E4BP4 transfected 293: sc-110510 (B) and Ramos (C) whole cell lysates.

E4BP4 (B-1) - sc-137163 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
E4BP4 (B-1): sc-137163. Western blot analysis of E4BP4 expression in non-transfected: sc-110760 (A) and human E4BP4 transfected: sc-110510 (B) 293 whole cell lysates.

E4BP4 (C-18) - sc-9550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
E4BP4 (C-18): sc-9550. Western blot analysis of E4BP4 expression in Ramos whole cell lysate.

E4BP4 (F-1) - sc-74414 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
E4BP4 (F-1): sc-74414. Western blot analysis of E4BP4 expression in Ramos (A) and PCEP-4 (B) whole cell lysates.

E4BP4 (V-19) - sc-9549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
E4BP4 (V-19): sc-9549. Western blot analysis of E4BP4 expression in non-transfected: sc-110760 (A) and human E4BP4 transfected: sc-110510 (B) 293 whole cell lysates.

E4BP4 (A-9) - sc-74415 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
E4BP4 (A-9): sc-74415. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

E4BP4 (H-300) - sc-28203 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
E4BP4 (H-300): sc-28203. Western blot analysis of E4BP4 expression in non-transfected: sc-110760 (A) and human E4BP4 transfected: sc-110510 (B) 293 whole cell lysates.

Anti-NFIL3 antibody - ab93785 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NFIL3 antibody (ab93785) at 0.4 µg/mlLane 1 : Whole cell lysate from HeLa cells at 50 µgLane 2 : Whole cell lysate from HeLa cells at 15 µgLane 3 : Whole cell lysate from HeLa cells at 5 µgdeveloped using the ECL technique

Anti-NFIL3 antibody - ab66004 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NFIL3 antibody (ab66004) at 1/500 dilutionLane 1 : Extracts from 293 cells at 5-30ugLane 2 : Extracts from K562 cells at 5-30ugLane 3 : Extracts from K562 cells at 5-30ug with immunizing peptide at 5-10ug

Anti-NFIL3 antibody - ab88526 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NFIL3 antibody (ab88526) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-NFIL3 antibody - ab130726 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-NFIL3 antibody (ab130726) at 1/100 dilution + MCF-7 cell lysate at 35 µg

Anti-NFIL3 antibody - ab1078 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-NFIL3 antibody (ab1078) at 0.5 µg/ml + Cell lysate prepared from HepG2 cells at 20 µgdeveloped using the ECL technique

Anti-NFIL3 Antibody (Glu65) - LS-C191984 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NFIL3 Antibody (aa46-74, AP) - LS-C264298 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NFIL3 Antibody (aa46-74, APC) - LS-C264299 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NFIL3 Antibody (N-Terminus) - LS-C31097 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Transfected 293T Cell Lysate

Anti-NFIL3 Antibody (aa449-462) - LS-C55174 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (2 ug/ml) of Daudi lysate (RIPA buffer, 20 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-NFIL3 Antibody (aa46-74, Biotin) - LS-C264300 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NFIL3 Antibody (aa46-74, FITC) - LS-C264301 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NFIL3 Antibody (aa46-74, Azide-free, HRP) - LS-C264302 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NFIL3 Antibody (aa46-74, PE) - LS-C264303 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NFIL3 Antibody (aa412-462) - LS-C289338 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NFIL3 Antibody (aa45-74) - LS-C323315 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NFIL3 Antibody (aa254-303) - LS-C79956 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.
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