| Gene Symbol |
KLLN
|
| Entrez Gene |
100144748
|
| Alt Symbol |
CWS4, KILLIN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
killin, p53-regulated DNA replication inhibitor
|
| Other Description |
killin
|
| Swissprots |
B2CW77
|
| Accessions |
B2CW77 EU552092 ACB45456 NM_001126049 NP_001119521
|
| Function |
DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single- stranded DNA. {ECO:0000269|PubMed:18385383}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:18385383}.
|