Gene Symbol | KLLN |
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Entrez Gene | 100144748 |
Alt Symbol | CWS4, KILLIN |
Species | Human |
Gene Type | protein-coding |
Description | killin, p53-regulated DNA replication inhibitor |
Other Description | killin |
Swissprots | B2CW77 |
Accessions | B2CW77 EU552092 ACB45456 NM_001126049 NP_001119521 |
Function | DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single- stranded DNA. {ECO:0000269|PubMed:18385383}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18385383}. |
KILLIN CRISPR/Cas9 KO Plasmid (h) - sc-410670 from Santa Cruz Biotechnology
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KILLIN HDR Plasmid (h) - sc-410670-HDR from Santa Cruz Biotechnology
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KILLIN Double Nickase Plasmid (h) - sc-410670-NIC from Santa Cruz Biotechnology
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KILLIN Double Nickase Plasmid (h2) - sc-410670-NIC-2 from Santa Cruz Biotechnology
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KILLIN CRISPR Activation Plasmid (h) - sc-410670-ACT from Santa Cruz Biotechnology
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KILLIN CRISPR Activation Plasmid (h2) - sc-410670-ACT-2 from Santa Cruz Biotechnology
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KILLIN Lentiviral Activation Particles (h) - sc-410670-LAC from Santa Cruz Biotechnology
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KILLIN Lentiviral Activation Particles (h2) - sc-410670-LAC-2 from Santa Cruz Biotechnology
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KILLIN siRNA (h) - sc-270305 from Santa Cruz Biotechnology
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KILLIN shRNA Plasmid (h) - sc-270305-SH from Santa Cruz Biotechnology
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KILLIN shRNA (h) Lentiviral Particles - sc-270305-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11214 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11214 from Sigma-Aldrich
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KLLN siRNA (Human) - CRJ8844 from Cohesion Biosciences
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shRNA set against Human KLLN (NM_001126049.1) - SHH326671 from Creative biogene
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KLLN shRNA Plasmid (Human) - CHJ8844 from Cohesion Biosciences
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