| Gene Symbol |
TAS2R38
|
| Entrez Gene |
5726
|
| Alt Symbol |
PTC, T2R38, T2R61
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
taste receptor, type 2, member 38
|
| Other Description |
PTC bitter taste receptor|taste receptor type 2 member 38|taste receptor type 2 member 61
|
| Swissprots |
A4D1U6 Q645W3 P59533 Q86UK3 Q2M3E8 P59552
|
| Accessions |
AAM19322 AAM63545 AAP14666 AAP14667 AFH77562 BAD98025 BAD98026 BAD98027 CAI53572 CAI53575 EAL24011 EAW83993 P59533 BC104933 AAI04934 BC104937 AAI04938 NM_176817 NP_789787
|
| Function |
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
|
| Top Pathways |
Taste transduction
|
