| Gene Symbol |
RHCG
|
| Entrez Gene |
51458
|
| Alt Symbol |
C15orf6, PDRC2, RHGK, SLC42A3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rh family, C glycoprotein
|
| Other Description |
Rh type C glycoprotein|Rhesus blood group, C glycoprotein|ammonium transporter Rh type C|rh family type C glycoprotein|rh glycoprotein kidney|rhesus blood group family type C glycoprotein|tumor-related protein DRC2
|
| Swissprots |
Q6X3Y4 Q9UBD6 A8K4D4
|
| Accessions |
AAG02171 AAG02414 EAX02051 EAX02052 Q9UBD6 AF081497 AAD55748 AF193809 AAF19372 AK290899 BAF83588 AK298252 BAG60517 AK298641 BAG60816 AK301640 BAG63121 AK310222 AK313238 BAG36049 AY257182 AAP81044 BC015461 BC030965 AAH30965 DC306265 XM_011521663 XP_011519965 NM_016321 NP_057405 NR_110261
|
| Function |
Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion. {ECO:0000269|PubMed:11062476, ECO:0000269|PubMed:14761968, ECO:0000269|PubMed:15929723, ECO:0000269|PubMed:16477434}.
|
| Subcellular Location |
Apical cell membrane {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:12204676}; Multi- pass membrane protein {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:12204676}. Note=Also detected at the basolateral membrane and in subapical vesicles. {ECO:0000250}.
|
| Tissue Specificity |
Expressed in brain, testis, placenta, pancreas, esophagus and prostate. Expressed in squamous epithelial tissues (at protein level). According to PubMed:11062476, specifically expressed in kidney. {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:11062476, ECO:0000269|PubMed:12204676}.
|
![Western Blot: RHCG Overexpression Lysate (Adult Normal) [NBP2-07055] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RHCG.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4795_RHCG%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07055-img0001.jpg)