Gene Symbol | RHCG |
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Entrez Gene | 51458 |
Alt Symbol | C15orf6, PDRC2, RHGK, SLC42A3 |
Species | Human |
Gene Type | protein-coding |
Description | Rh family, C glycoprotein |
Other Description | Rh type C glycoprotein|Rhesus blood group, C glycoprotein|ammonium transporter Rh type C|rh family type C glycoprotein|rh glycoprotein kidney|rhesus blood group family type C glycoprotein|tumor-related protein DRC2 |
Swissprots | Q6X3Y4 Q9UBD6 A8K4D4 |
Accessions | AAG02171 AAG02414 EAX02051 EAX02052 Q9UBD6 AF081497 AAD55748 AF193809 AAF19372 AK290899 BAF83588 AK298252 BAG60517 AK298641 BAG60816 AK301640 BAG63121 AK310222 AK313238 BAG36049 AY257182 AAP81044 BC015461 BC030965 AAH30965 DC306265 XM_011521663 XP_011519965 NM_016321 NP_057405 NR_110261 |
Function | Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion. {ECO:0000269|PubMed:11062476, ECO:0000269|PubMed:14761968, ECO:0000269|PubMed:15929723, ECO:0000269|PubMed:16477434}. |
Subcellular Location | Apical cell membrane {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:12204676}; Multi- pass membrane protein {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:12204676}. Note=Also detected at the basolateral membrane and in subapical vesicles. {ECO:0000250}. |
Tissue Specificity | Expressed in brain, testis, placenta, pancreas, esophagus and prostate. Expressed in squamous epithelial tissues (at protein level). According to PubMed:11062476, specifically expressed in kidney. {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:11062476, ECO:0000269|PubMed:12204676}. |
RhCG CRISPR/Cas9 KO Plasmid (h) - sc-407579 from Santa Cruz Biotechnology
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RhCG HDR Plasmid (h) - sc-407579-HDR from Santa Cruz Biotechnology
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RhCG Double Nickase Plasmid (h) - sc-407579-NIC from Santa Cruz Biotechnology
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RhCG Double Nickase Plasmid (h2) - sc-407579-NIC-2 from Santa Cruz Biotechnology
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RhCG CRISPR Activation Plasmid (h) - sc-407579-ACT from Santa Cruz Biotechnology
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RhCG CRISPR Activation Plasmid (h2) - sc-407579-ACT-2 from Santa Cruz Biotechnology
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RhCG Lentiviral Activation Particles (h) - sc-407579-LAC from Santa Cruz Biotechnology
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RhCG Lentiviral Activation Particles (h2) - sc-407579-LAC-2 from Santa Cruz Biotechnology
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RhCG siRNA (h) - sc-90218 from Santa Cruz Biotechnology
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RhCG shRNA Plasmid (h) - sc-90218-SH from Santa Cruz Biotechnology
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RhCG shRNA (h) Lentiviral Particles - sc-90218-V from Santa Cruz Biotechnology
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RHCG RNAi - H00051458-R01 from Novus Biologicals
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MISSION® esiRNA - EHU029921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18247 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18247 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03438 from Sigma-Aldrich
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RHCG siRNA (Human) - CRH9775 from Cohesion Biosciences
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RHCG - MBS8216962 from MyBioSource
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shRNA set against Human RHCG (NM_016321.1) - SHH395204 from Creative biogene
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shRNA set against Human RHCG(NM_016321.1) - SHR180462 from Creative biogene
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RHCG shRNA Plasmid (Human) - CHH9775 from Cohesion Biosciences
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RHCG miRNA 3'UTR clone - MiUTR1H-08805 from Creative biogene
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