Gene Symbol | CACNG4 |
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Entrez Gene | 27092 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | calcium channel, voltage-dependent, gamma subunit 4 |
Other Description | TARP gamma-4|neuronal voltage-gated calcium channel gamma-4 subunit|transmembrane AMPAR regulatory protein gamma-4|voltage-dependent calcium channel gamma-4 subunit |
Swissprots | Q9UBN1 B2RCK0 |
Accessions | AAF03090 EAW89020 EAW89021 Q9UBN1 AF162692 AAF14538 AK055232 AK315149 BAG37597 AL526464 AL713655 CAD28464 AL831834 BC004504 BC032765 BC034532 AAH34532 BF508806 DQ891815 ABM82741 DQ895000 ABM85926 NM_014405 NP_055220 |
Function | Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. {ECO:0000269|PubMed:21172611}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
CACNG4 Antibody Blocking Peptide - LS-E2007 from LifeSpan Bioscience
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CACNG4 Antibody Blocking Peptide - LS-E13516 from LifeSpan Bioscience
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CACNG4-Antibody-Center-Blocking-peptide - BP12867c from Abgent, a WuXi AppTec company
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CACNG4 Blocking Peptide - 33R-3479 from Fitzgerald
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CACNG4 Blocking Peptide - 33R-3480 from Fitzgerald
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CACNG4 fusion protein - ag11200 from Proteintech Group
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CACNG4 fusion protein - Ag11191 from Proteintech Group
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Recombinant Human CACNG4, GST-tagged - CACNG4-10644H from Creative Biomart
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CACNG4 Protein - abx163420 from Abbexa
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CACNG4 Protein - NBP2-31835PEP from Novus Biologicals
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CACNG4 Peptide, Human - M34GP02273H from Creative Peptides
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CACNG4 Recombinant Protein Antigen - NBP2-55863PEP from Novus Biologicals
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CACNG4 Recombinant Protein Antigen - NBP2-55176PEP from Novus Biologicals
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