Gene Symbol | KRTAP12-4 |
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Entrez Gene | 386684 |
Alt Symbol | KRTAP12.4 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 12-4 |
Other Description | high sulfur keratin-associated protein 12.4|keratin-associated protein 12-4 |
Swissprots | Q08AF5 P60329 |
Accessions | EAX09408 P60329 AB076360 BAD01547 BC125198 AAI25199 NM_198698 NP_941971 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. {ECO:0000269|PubMed:14962103, ECO:0000269|PubMed:15028290}. |
Recombinant Human KRTAP12-4 - KRTAP12-4-1551H from Creative Biomart
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Recombinant Human Keratin-associated protein 12-4(KRTAP12-4) - CSB-YP012608HU CSB-EP012608HU CSB-BP012608HU CSB-MP012608HU from Cusabio
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KRTAP12-4 Peptide, Human - M34GP08427H from Creative Peptides
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Keratin-associated protein 12-4 (KRTAP12-4), Recombinant Protein - MBS968141 from MyBioSource
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