SLC14A1

Gene Symbol	SLC14A1
Entrez Gene	6563
Alt Symbol	HUT11, HsT1341, JK, RACH1, RACH2, UT-B1, UT1, UTE
Species	Human
Gene Type	protein-coding
Description	solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
Other Description	Kidd blood group|SLC14A1 JK|urea transporter 1|urea transporter JK glycoprotein|urea transporter, erythrocyte|urea transporter-B1
Swissprots	B3KVX3 C9EHF2 A8K0P3 Q86VM5 Q13336 B3KR62
Accessions	AAC69610 AAD43502 AAL37474 AAX20112 AEG64823 AEG64824 AEG64825 AEG64826 AEG64827 AEN14346 AEN14347 AFC36888 AFC36889 AFC36890 AFN89220 AFN89221 AFN89222 AIL24477 AIN41649 CAC86943 CCD04138 CDR98193 CDR98194 CDR98195 EAX01458 EAX01459 Q13336 AF263545 AF328892 AK091064 BAG52274 AK123681 BAG53935 AK127452 BAG54505 AK289608 BAF82297 AK294129 BAG57459 AK295268 BAG58255 AU134365 AV724913 BC040128 BC050539 AAH50539 DA051199 DA134800 DA156178 DA186606 DA473671 GQ502682 ACV91713 HQ709264 ADW41579 KC677694 AGN03946 L36121 U35735 AAB00181 Y19039 CAB60834 XM_005258329 XP_005258386 XM_005258332 XP_005258389 XM_005258333 XP_005258390 XM_006722526 XP_006722589 XM_011526141 XP_011524443 XM_011526142 XP_011524444 XM_011526143 XP_011524445 XM_011526144 XP_011524446 NM_001128588 NP_001122060 NM_001146036 NP_001139508 NM_001146037 NP_001139509 NM_001308278 NP_001295207 NM_001308279 NP_001295208 NM_015865 NP_056949
Function	Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:23219802}; Multi-pass membrane protein {ECO:0000269|PubMed:23219802}. Basolateral cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Restricted to the basolateral membrane in various portions of the urothelium. {ECO:0000250}.
Tissue Specificity	Detected in erythrocytes (at protein level). Erythrocytes. {ECO:0000269|PubMed:23219802}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SLC14A1 293T Cell Transient Overexpression Lysate(Denatured) - H00006563-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SLC14A1 overexpression lysate - LY426961 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SLC14A1 overexpression lysate - LY431384 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SLC14A1 293 Cell Lysate - 402157 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Tissue Blood

SLC14A1 Overexpression Lysate (Denatured) - H00006563-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

SLC14A1 Overexpression Lysate (Native) - NBL1-16011 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SLC14A1 Over-expression Lysate Product - GWB-E0128F from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

SLC14A1 Overexpression Lysate (Native) - NBP2-10195 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SLC14A1 Overexpression Lysate (Native) - NBP2-10148 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SLC14A1 Overexpression Lysate (Native) - NBP2-09479 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SLC14A1 Overexpression Lysate (Denatured) - H00006563-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human SLC14A1 Knockdown Stable Cell Line - CSC-DC014328 from Creative biogene Category Cell Line Species Human

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