SLC14A1

Gene Symbol SLC14A1
Entrez Gene 6563
Alt Symbol HUT11, HsT1341, JK, RACH1, RACH2, UT-B1, UT1, UTE
Species Human
Gene Type protein-coding
Description solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
Other Description Kidd blood group|SLC14A1 JK|urea transporter 1|urea transporter JK glycoprotein|urea transporter, erythrocyte|urea transporter-B1
Swissprots B3KVX3 C9EHF2 A8K0P3 Q86VM5 Q13336 B3KR62
Accessions AAC69610 AAD43502 AAL37474 AAX20112 AEG64823 AEG64824 AEG64825 AEG64826 AEG64827 AEN14346 AEN14347 AFC36888 AFC36889 AFC36890 AFN89220 AFN89221 AFN89222 AIL24477 AIN41649 CAC86943 CCD04138 CDR98193 CDR98194 CDR98195 EAX01458 EAX01459 Q13336 AF263545 AF328892 AK091064 BAG52274 AK123681 BAG53935 AK127452 BAG54505 AK289608 BAF82297 AK294129 BAG57459 AK295268 BAG58255 AU134365 AV724913 BC040128 BC050539 AAH50539 DA051199 DA134800 DA156178 DA186606 DA473671 GQ502682 ACV91713 HQ709264 ADW41579 KC677694 AGN03946 L36121 U35735 AAB00181 Y19039 CAB60834 XM_005258329 XP_005258386 XM_005258332 XP_005258389 XM_005258333 XP_005258390 XM_006722526 XP_006722589 XM_011526141 XP_011524443 XM_011526142 XP_011524444 XM_011526143 XP_011524445 XM_011526144 XP_011524446 NM_001128588 NP_001122060 NM_001146036 NP_001139508 NM_001146037 NP_001139509 NM_001308278 NP_001295207 NM_001308279 NP_001295208 NM_015865 NP_056949
Function Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.
Subcellular Location Cell membrane {ECO:0000269|PubMed:23219802}; Multi-pass membrane protein {ECO:0000269|PubMed:23219802}. Basolateral cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Restricted to the basolateral membrane in various portions of the urothelium. {ECO:0000250}.
Tissue Specificity Detected in erythrocytes (at protein level). Erythrocytes. {ECO:0000269|PubMed:23219802}.

UT-B (H-40) - sc-368104 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

UT-B (C-19) - sc-85203 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

UT-B (N-20) - sc-85205 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

UT-B (O-24) - sc-134144 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
UT-B (O-24): sc-134144. Western blot analysis of UT-B expression in non-transfected 293T: sc-117752 (A), mouse UT-B transfected 293T: sc-124504 (B) and HEL 92.1.7 (C) whole cell lysates.

Anti-SLC14A1 antibody - ab103295 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC14A1 antibody (ab103295) at 1/500 dilution + Mouse liver tissue lysate at 50 µg

Anti-SLC14A1 antibody - ab67595 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SLC14A1 antibody (ab67595) at 1/500 dilutionLane 1 : SLC14A1 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg/ml per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-SLC14A1 antibody - N-terminal - ab198743 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SLC14A1 antibody - N-terminal (ab198743) at 1/200 dilution + Mouse kidney tissue lysate at 40 µg

Anti-SLC14A1 / JK Antibody (aa119-168) IHC-plus™ - LS-B9722 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC14A1 / JK antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9722 concentration 5 ug/ml.

Anti-SLC14A1 / JK Antibody (aa1-389) - LS-C132158 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC14A1 / JK Antibody - LS-C296922 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC14A1 / JK Antibody (FITC) - LS-C305499 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC14A1 / JK Antibody (Biotin) - LS-C305819 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SLC14A1 Antibody - NBP2-31781 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SLC14A1 Antibody [NBP2-31781] - Staining of liver cancer.

SLC14A1 Antibody - NBP1-60115 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLC14A1 Antibody (888418) - MAB8238 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 888418

SLC14A1 Antibody - H00006563-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SLC14A1 Antibody [H00006563-D01P] - Analysis of SLC14A1 expression in mouse liver.

SLC14A1 Antibody - H00006563-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLC14A1 Antibody - H00006563-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SLC14A1 Antibody [H00006563-B01P] - Analysis of SLC14A1 expression in transfected 293T cell line by SLC14A1 polyclonal antibody. Lane 1: SLC14A1 transfected lysate(42.79 KDa). Lane 2: Non-transfected lysate.

SLC14A1 Antibody (888418) [Allophycocyanin] - FAB8238A from Novus Biologicals

Prices $349.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 888418
Human red blood cells were stained with Mouse Anti-Human SLC14A1 APC-conjugated Mono­clonal Antibody (Catalog # FAB8238A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.

SLC14A1 Antibody (888418) [Phycoerythrin] - FAB8238P from Novus Biologicals

Prices $309.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 888418
Human red blood cells were stained with Mouse Anti-Human SLC14A1 PE-conjugated Monoclonal Antibody (Catalog # FAB8238P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.

SLC14A1 Polyclonal Antibody - bs-7639R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC14A1 antibody produced in mouse - SAB1406449 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SLC14A1: <B>Cat. No. SAB1406449</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~42.8 kDa using SLC14A1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-SLC14A1 antibody produced in rabbit - SAB1401365 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-SLC14A1, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401365</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~42.1 kDa using mouse liver lysate.

Anti-SLC14A1 antibody produced in rabbit - AV48116 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC14A1: <B>Cat. No. AV48116</B>: Immunohistochemistry of SLC14A1 in Human Kidney tissue with SLC14A1 antibody at 4-8 μg/mL.

SLC14A1 antibody - C-terminal region (ARP48116_P050) - ARP48116_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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